gene therapy

(redirected from Antibody genes)
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gene therapy

n.
The treatment of certain medical disorders, especially those caused by genetic anomalies or deficiencies, by introducing specific engineered genes into a patient's cells.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

gene therapy

n
(Genetics) the replacement or alteration of defective genes in order to prevent the occurrence of such inherited diseases as haemophilia. Effected by genetic engineering techniques, it is still at the experimental stage
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

gene′ ther`apy


n.
the treatment of a disease by replacing aberrant genes with normal ones, esp. through the use of viruses to transport the desired genes into the nuclei of blood cells.
[1970–75]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.

gene therapy

The treatment of disease, especially one caused by the inheritance of a defective gene, by replacing defective genes with healthy ones through genetic engineering.
The American Heritage® Student Science Dictionary, Second Edition. Copyright © 2014 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
Translations
thérapie génique
génterápia

gene therapy

n (Med) → Gentherapie f
Collins German Dictionary – Complete and Unabridged 7th Edition 2005. © William Collins Sons & Co. Ltd. 1980 © HarperCollins Publishers 1991, 1997, 1999, 2004, 2005, 2007
References in periodicals archive ?
They added their huge library of antibody genes to the population of cells: each cell ended up containing the genes for one or more of the antibodies.
In addition to the antibody genes and those encoding the Cas9 enzyme and guide RNA, the researchers inserted a gene that would cause mosquitoes' eyes to glow red under fluorescent lights, enabling the team to easily find insects of interest.
These antibodies are part of animal immune systems while plantibody is an antibody produced by genetically modified crops and are produced in plants by transforming them with antibody genes from animals.
AID is best known as a master regulator of antibody diversity in B cells, and in order to create varied types of beneficial antibodies, it routinely mutates antibody genes. But sometimes the process goes awry, resulting in development of B cell lymphoma, Evans said.
They had low levels of inflammatory gene expression and strong expression of antiviral and antibody genes.
They have discovered that a good number of our antibody genes, how well they operate and, potentially, what they fight off, actually vary from person to person.
Research suggested that GANP is important in the reconstruction of antibody genes. Transgenic mice which express high level of GANP can be used to produce antibodies with a high affinity.
This would require either a huge amount of genome devoted to antibody genes, or a diversity generation mechanism.
The resulting antigenized antibody genes were cloned into mammalian expression vector.
To investigate the molecular basis for DNA recognition by lupus autoantibodies, antibody genes from a large number of human and murine anti-DNA antibodies from hybridomas have been characterized.
Human antibody-producing cows, containing full-length human antibody genes, are expected to prove useful for the development of a range of human antibody-based drugs.