antigen

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Related to Antigen presentation: clonal expansion, antigen recognition

an·ti·gen

 (ăn′tĭ-jən) also an·ti·gene (-jēn′)
n.
A molecule that is capable of binding to an antibody or to an antigen receptor on a T cell, especially one that induces an immune response. An antigen is usually a foreign substance, such as a toxin or a component of a virus, bacterium, or parasite.

an′ti·gen′ic (-jĕn′ĭk) adj.
an′ti·gen′i·cal·ly adv.
an′ti·ge·nic′i·ty (-jə-nĭs′ĭ-tē) n.

antigen

(ˈæntɪdʒən; -ˌdʒɛn) or

antigene

n
(Biochemistry) a substance that stimulates the production of antibodies
[C20: from anti(body) + -gen]
ˌantiˈgenic adj
ˌantiˈgenically adv

an•ti•gen

(ˈæn tɪ dʒən, -ˌdʒɛn)

n.
1. any substance that can stimulate the production of antibodies and combine specifically with them.
2. any commercial substance that, when injected or absorbed into animal tissues, stimulates the production of antibodies.
3. antigens of a particular type collectively.
[1905–10; anti (body) + -gen]
an`ti•gen′ic, adj.
an`ti•gen′i•cal•ly, adv.
an`ti•ge•nic′i•ty (-dʒəˈnɪs ɪ ti) n.

an·ti·gen

(ăn′tĭ-jən)
A substance that stimulates the production of an antibody when introduced into the body. Antigens include toxins, bacteria, viruses, and other foreign substances. See Note at blood type.

antigen

A molecule recognized as foreign by the body’s immune system, causing the release of antibodies.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.antigen - any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)
substance - a particular kind or species of matter with uniform properties; "shigella is one of the most toxic substances known to man"
immunizing agent, immunogen - any substance or organism that provokes an immune response (produces immunity) when introduced into the body
immunology - the branch of medical science that studies the body's immune system
agglutinogen - any substance that acts as an antigen to cause agglutinin production
fetoprotein, foetoprotein - any of several antigens that occur naturally in the fetus and sometimes in adults with cancer
anatoxin, toxoid - a bacterial toxin that has been weakened until it is no longer toxic but is strong enough to induce the formation of antibodies and immunity to the specific disease caused by the toxin; "diphtheria toxoid"
antigenic determinant, epitope, determinant - the site on the surface of an antigen molecule to which an antibody attaches itself
Rh, Rh factor, rhesus factor - a blood group antigen possessed by Rh-positive people; if an Rh-negative person receives a blood transfusion from an Rh-positive person it can result in hemolysis and anemia
Translations
antigen
antigeeni
antigén
antígeno
antigen
antigen

antigen

[ˈæntɪdʒən] Nantígeno m

antigen

[ˈæntɪdʒən] nantigène manti-hero antihero [ˈæntihɪərəʊ] nantihéros m

antigen

nAntigen nt

antigen

[ˈæntɪdʒən] nantigene m

an·ti·gen

n. antígeno, sustancia tóxica que estimula la formación de anticuerpos;
carcinoembriogenic ______ carcinoembriogénico.

antigen

n antígeno; carcinoembryonic — antígeno carcinoembrionario; prostate-specific — (PSA) antígeno prostático específico (APE)
References in periodicals archive ?
Antigen presentation by DCs specifically activates T cells reactive to the antigen, and activated T cells then interact with B lymphocytes (B cells) that are stimulated by the same antigen.
The company's peptide- or nucleic acid-based immunotherapeutic products comprise multiple naturally processed epitopes designed to comprehensively stimulate a patient's killer T cells and helper T cells, and to restore or further augment antigen presentation by using proprietary nucleic acid-based expression systems.
sup][5] In TAP knockout cells, the antigenic peptides were not effectively transported into the endoplasmic reticulum to abolish endogenous antigen presentation.
One of these checkpoints is antigen presentation, which is accomplished primarily by mature dendritic cells.
Since the specific interactions between T cells and macrophages have been measured in a short (5 to 15 minutes) time period [23], we used an average value of 10 minutes to calculate the MHC II antigen presentation rate, giving a rate of 6 [h.
Therefore, it has become pivotal to understand the properties of CD1 molecules, the mechanism of CD1-mediated lipid antigen presentation, and the biology of CD1-restricted T cells, to develop new strategies to control infection and cancer.
In addition, Dx inhibits the antigen presentation of DCs [8].
Such findings could be associated with persistent antigen presentation to [CD4.
By targeting tumor antigen presentation, MEDI9197 adds a unique mechanism of immune activation to our growing portfolio and supports our strategy of maximizing anti-tumor immunity through scientifically rational combinations.
Basic science studies indicate that statins are associated with amelioration of disease in mouse models of IBD, may decrease mediators of inflammation, such as tumor necrosis factor-alpha, and may also suppress antigen presentation and T-cell proliferation, he noted.
The volume then turns to research on physiological functions of endocytosis including autophagy, neural signaling, antigen presentation, developmental signaling, and evolutionary roots.