antigenic determinant

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antigenic determinant

(Biochemistry) the specific part of an antigen molecule to which an antibody becomes attached


(ˈɛp ɪˌtoʊp)

a site on an antigen at which an antibody can bind, the molecular arrangement of the site determining the specific combining antibody. Also called antigenic determinant .
[1970–75; epi- + -tope < Greek tópos place; compare topo-]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.antigenic determinant - the site on the surface of an antigen molecule to which an antibody attaches itself
immunology - the branch of medical science that studies the body's immune system
site, situation - physical position in relation to the surroundings; "the sites are determined by highly specific sequences of nucleotides"
antigen - any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)
References in periodicals archive ?
However, in the United Kingdom, HFRS cases with serologic cross-reactivity to PUUV (3), which might share antigenic determinants with Tatenale virus, have occurred.
Recombinant core particles of hepatitis B virus exposing foreign antigenic determinants on their surface.
Use of multiple antigenic peptides related to antigenic determinants of infectious bursal disease virus (IBDV) for detection of anti- IBDV-specific antibody in ELISA-quantitative comparison with native antigen for their use in serodiagnosis.
Full length Hexon carries type, group and subgroup specific antigenic determinants, whereas, hypervariable region of hexon contains type specific antigenic regions.
RED BLOOD CELLS CONCENTRATE (SERASCAN) (vial presentation (I and II) with 10 ml of human erythrocytes group 0, with more significant antigenic determinants of most of the blood group systems.
Langerhans cells have cytoplasmic inclusion bodies known as Birbeck granules; a definitive diagnosis requires electron microscopy of Birbeck granules or CD 1 antigenic determinants by immunohistochemistry.
The four prominent antigenic determinants were identified in the sequence also corresponded to the residues 13-20, 24-34, 199-210 and 230-239 (Figure 6B, Table 1).
These include developing highly specific immunogens that mimic the antigenic determinants recognized by broadly neutralizing antibodies found in infected people.
Analysis of the antigenic determinants of the mannan of Candida albicans serotype B-792.