antigenic determinant

(redirected from Antigenic determinants)
Also found in: Thesaurus, Medical, Encyclopedia.

antigenic determinant

(Biochemistry) the specific part of an antigen molecule to which an antibody becomes attached


(ˈɛp ɪˌtoʊp)

a site on an antigen at which an antibody can bind, the molecular arrangement of the site determining the specific combining antibody. Also called antigenic determinant .
[1970–75; epi- + -tope < Greek tópos place; compare topo-]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.antigenic determinant - the site on the surface of an antigen molecule to which an antibody attaches itself
immunology - the branch of medical science that studies the body's immune system
site, situation - physical position in relation to the surroundings; "the sites are determined by highly specific sequences of nucleotides"
antigen - any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)
References in periodicals archive ?
Cell surface markers are a protein or antigenic determinants, which are found on the surface of precise types of cells.
These residues with high frequencies of occurrences in antigenic determinants were highlighted (yellow) in the antigenicity profile (fig.
However, in the United Kingdom, HFRS cases with serologic cross-reactivity to PUUV (3), which might share antigenic determinants with Tatenale virus, have occurred.
This base could expose the sugar epitopes, leaving them available as antigenic determinants to induce specific IgE production [4,9].
A specific antibody (Ab) recognizes antigen (Ag) at discrete regions known as antigenic determinants or B-cell epitopes.
In Figure 7(1B), the two peaks of antigenicity are located on the surface of the protein with higher score in green color and, additionally, its active center in red color is observed, corresponding to the information registered on the antigenic determinants in Table 5.
Recombinant core particles of hepatitis B virus exposing foreign antigenic determinants on their surface.
Full length Hexon carries type, group and subgroup specific antigenic determinants, whereas, hypervariable region of hexon contains type specific antigenic regions.
Langerhans cells have cytoplasmic inclusion bodies known as Birbeck granules; a definitive diagnosis requires electron microscopy of Birbeck granules or CD 1 antigenic determinants by immunohistochemistry.