In a small retrospective study, 85% of patients treated with the oral antimalarial agent
had marked improvement or full remission, according to Ziyad Khamaysi, MD, a dermatologist at Rambam Health Care Campus, Haifa, Israel.
HCQ is an antimalarial agent
. The reported effects of antimalarials include antimicrobial, antithrombotic, metabolic and cardiovascular, antineoplastic, and others.
papaya fruit rind had the highest antimalarial activity and could be targeted as potential source of lead compound in the development of new antimalarial agent
. Therefore, further study should be done on pet ether fraction of C.
In addition, the introduction of an amide bond with a heterocyclic ring system (4-thiazolidine) to the lateral side chain of 4-aminoquinoline (an antimalarial agent
) has been shown to improve the antimalarial activity of this compound .
A recent analysis of five clinical trials to assess the safety and tolerability of an investigational antimalarial agent
, Tafenoquine, has been published in Travel Medicine and Infectious Disease, a peer-reviewed journal.
Initially acridine analogs were clinically utilized as antimicrobials and antimalarial agent
in early and middle nineteen century in which amino derivatives of acridine mainly acriflavine, trypaflavin, gonoflavin and proflavine were mostly used, later quinacrine was used as antiseptics in hospitals till the discovery of penicillins as antibiotic agents .
Eisai is also conducting a Phase I clinical trial of antimalarial agent
SJ733 in collaboration with non-profit public-private partnership Medicines for Malaria Venture (MMV) and the University of Kentucky.
Edrada-Ebel, "Gancidin W, a potential low-toxicity antimalarial agent
isolated from an endophytic Streptomyces SUK10," Drug Design, Development and Therapy, vol.
Plasma concentrations of tafenoquine, a new long-acting antimalarial agent
, in Thai soldiers on monthly prophylaxis.
It is always important to prescribe a prophylactic antimalarial agent
, but even more prudent to prescribe the appropriate drug and dosage.
Poljakov collected in the Province of Khorassan (Iran) afforded, in addition to several eudesmanolides, a new type of sesquiterpene lactone (Tehranolide) (20), with anendoperoxide group that probably has the same effect as the antimalarial agent
The emergence of resistance of malarial parasites to traditional antimalarials sends an urgent signal for a safe, effective, nontoxic, and cost-effective antimalarial agent
, and MagNascent fits the bill and can serve as a promising agent superior to chloroquine, quinine, pyrimethamine, and artemisinin.