Molecular pathogenesis of the antiphospholipid syndrome
sup] Antiphospholipid syndrome
(APS) is a group of diseases characterized by RSA, stillbirth, premature birth, and serum antiphospholipid antibodies (APL).
Venous thrombosis, especially deep venous thrombosis of the legs, is the most common manifestation of the antiphospholipid syndrome
occurring in 29 to 55 percent of patients with the syndrome during an average followup of less than six years.
Group one included SLE without antiphospholipid syndrome
(APS) and group two SLE with APS.
(APS) is a systemic autoimmune disorder defined by the occurrence of recurrent vascular (venous and arterial) thrombosis and pregnancy morbidity in the presence of persistently elevated antiphospholipid antibodies (aPL), anticardiolipin IgG/ IgM, lupus anticoagulant and anti-[beta]2-glycoprotein-1 IgG/IgM.
Objectives: The aim of this study was to evaluate the prevalence of subclinical and clinical iron deficiency with iron deficiency anemia in primary antiphospholipid syndrome
When she was 22 weeks pregnant she was diagnosed with antiphospholipid syndrome
, more commonly known as sticky blood.
It would be useful to follow a cohort of patients affected by systemic scleroderma in order to monitor vascular complications following confirmation of the presence of antiphospholipid syndrome
They address definitions, the role of antiphospholipid syndrome
, screening and management of thrombophilia, the incidence of hyperhomocysteinemia, obesity, minimally invasive surgery for uterine pathology, bacterial vaginosis, endometritis, genetic causes, the role of in vitro fertilization, and preimplantation genetic screening.
Women with recurrent spontaneous abortions in the setting of antiphospholipid syndrome
have a 15-fold greater risk of thrombotic events over the long term, compared with women who have had multiple miscarriages but who don't have the syndrome.
Characteristics of patients with antiphospholipid syndrome
with major bleeding after oral anticoagulant treatment.