, also known as APAS or APS, is an autoimmune disorder where a person experiences a higher risk of blood clots.
Catastrophic antiphospholipid syndrome
in a patient with down syndrome.
Key words: Renal biopsy, antiphospholipid syndrome
nephropathy, lupus nephritis, thrombotic microangiopathy, systemic lupus erythematosus.
Primary biliary cirrhosis-autoimmune hepatitis overlap syndrome associated with dermatomyositis, autoimmune thyroiditis and antiphospholipid syndrome
. J Gastrointestin Liver Dis 2015; 24:101-4.
The pathogenesis of the antiphospholipid syndrome
. N Engl J Med 2013;368:1033-44.
We hypothesize that the patient's history of SLE, antiphospholipid syndrome
, and prolonged steroid use in the past 14 years contributed to his advanced atherosclerotic disease.
Truglia et al., "The mosaic of "seronegative" antiphospholipid syndrome
," Journal of Immunological Research, vol.
Espinosa et al., "Catastrophic antiphospholipid syndrome
: an orchestra with several musicians," Israel Medical Association Journal, vol.
As widespread thrombosis is the key feature of TS, it brings this syndrome closer to other clinical entities known for hypercoagulable states and extensive thrombotic events like Antiphospholipid Syndrome
(APS), Protein C and S Deficiency , Factor V Leiden, Heparin Induced Thrombocytopenia (HIT), Thrombocytopenic Purpura (TTP), and Hemolysis Elevated Liver enzymes and Low Platelets (HELLP) syndrome.
Hemorrhage has been described after surgery, such as cholecystectomy, total knee arthroplasty, duodenopancreatectomy, and vertebral surgery, in sepsis, and is rarely reported as a spontaneous event, mostly in pregnancy and in particular conditions such as polycythemia vera and antiphospholipid syndrome
An abstract version of the manuscript, under the title "Recurrent Nephrotic Syndrome with Two Different Natures of Glomerulopathy on a Case with Antiphospholipid Syndrome
" was presented at NKF 2016 Spring Clinical Meetings Abstracts.