antineoplastic

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an·ti·ne·o·plas·tic

 (ăn′tē-nē′ə-plăs′tĭk, ăn′tī-)
adj.
Inhibiting or preventing the growth or development of malignant cells.

an′ti·ne′o·plas′tic n.

antineoplastic

(ˌæntɪˌniːəʊˈplæstɪk)
adj
acting against tumours
n
a drug that acts against tumours

an•ti•ne•o•plas•tic

(ˌæn tiˌni oʊˈplæs tɪk, ˌæn taɪ-)

adj.
1. destroying, inhibiting, or preventing the growth or spread of tumors.
n.
2. an antineoplastic substance.
[1965–70]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.antineoplastic - any of several drugs that control or kill neoplastic cellsantineoplastic - any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function
alkylating agent - an antineoplastic drug used to treat some forms of cancer
antimetabolite - an antineoplastic drug that inhibits the utilization of a metabolite
antineoplastic antibiotic - an antibiotic drug used as an antineoplastic in chemotherapy
asparaginase, Elspar - antineoplastic drug (trade name Elspar) sometimes used to treat lymphoblastic leukemia
cytotoxic drug - any drug that has a toxic effect on cells; commonly used in chemotherapy to inhibit the proliferation of cancerous cells
floxuridine - antineoplastic drug used to treat some cancers; can cause loss of hair
lomustine - an antineoplastic drug often used to treat brain tumors or Hodgkin's disease
Alkeran, melphalan - antineoplastic drug (trade name Alkeran) used to treat multiple myeloma and some other malignancies
periwinkle plant derivative - an antineoplastic drug used to treat some forms of cancer
procarbazine - an antineoplastic drug used to treat Hodgkin's disease
thioguanine - an antineoplastic drug used to treat acute leukemias
thiotepa - an antineoplastic drug used to treat certain malignancies
Adj.1.antineoplastic - used in the treatment of cancerantineoplastic - used in the treatment of cancer; "anticancer drug"; "an antineoplastic effect"
Translations

an·ti·ne·o·plas·tic

a. antineoplástico-a, droga que controla o mata células cancerosas.
References in periodicals archive ?
Progesterone receptor antagonists and the endometrial antiproliferative effect.
Limenin did exhibit antiproliferative activity toward tumor cells, including human liver hepatoma cells Bel-7402 and certain neuroblastoma cells.
A smaller section is organized by biological activity, with chapters on plant families with potential antimicrobial, antiparasitic, antiproliferative, anti-inflammatory, anti-diabetes, antioxidant, and reproductive, cardiovascular, and nervous system activity.
The number of living cancer cells (cell viability) was measured, and it was shown that EGCG reduced cell viability in a dose-dependent fashion although at higher concentrations (0.15 mg/mL and above), the antiproliferative effect of EGCG in water was greater than in milk.
Subsequent studies by the same group indicated that extracts containing Quebecol might have an antiproliferative effect against colon cancer cells.
The results of predinical studies have suggested that statins may decrease the risk of cancers, perhaps because their antiproliferative, proapoptotic, antiangiogenic, immunomodulatory, and anti-in-fective effects may prevent cancer growth.
In detail, the inhibition of adenylyl cyclase activity and the reduction of intracellular [Ca.sup.2+] levels through the coordinated activities on different K.sup.+] and [Ca.sup.2+] channels, are responsible of the antisecretory effects of SST, while the activation of phosphotyrosine phosphatases (PTPs), and in particular of three enzymes of this family: Src-homology phosphatase type 1 (SHP-1) and type 2 (SHP-2), and density-enhanced phosphatase 1 (DEP-1)/PTP[eta], and the modulation of mitogen-activated protein kinase(MAPK) activity, are mainly responsible of SST antiproliferative effects [26-43].
We found that while RASSF1A reduced cell proliferation and further enhanced the antiproliferative effects of TNF-[alpha], RASSF1C significantly increased cell proliferation and reduced the antiproliferative effects of TNF-[alpha] on breast and lung cancer cells.
Other proposed mechanism for NO antiproliferative action is a G1-S inhibition mediated by an induction of the cell cycle inhibitor p21 [16] or cyclins inhibition [17].
Figure 3 demonstrates the antiproliferative effect of ethyl acetate fraction of V.
The constituents and antiproliferative effect of the fresh, dried and steamed gingers were then quantitatively compared.