antisense

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Related to Antisense strand: minus strand, plus strand

an·ti·sense

 (ăn′tē-sĕns′, ăn′tī-)
adj.
Of or relating to a nucleotide sequence that is complementary to a sequence of messenger RNA. When antisense DNA or RNA is added to a cell, it binds to a specific messenger RNA molecule and inactivates it.

an•ti•sense

(ˌæn tiˈsɛns, ˌæn taɪ-)
adj.
of or pertaining to a gene that is derived from RNA or complementary DNA, is inserted in reverse orientation into a strand of DNA, and is used in genetic engineering to regulate genetic expression of a trait.
[1985–90]
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References in periodicals archive ?
His partner was the complementary code on the antisense strand (TAC), the tRNA anticodon (UAC), and the corresponding amino acid (methionine).
Although most currently practiced methods of inducing the RNAi mechanism utilize double-stranded RNAs, RISC requires only the antisense strand to function.
The thermo-stability bias at the 5' end of the antisense strand: Since it is desirable to have only the antisense strand incorporated into the RISC complex, lowering the thermo-stability at the 5' end of the antisense strand can promote helicase unwind siRNA duplexes from this end [17,20,21].
In this technique, a complementary strand of RNA, the antisense strand, binds to part of a cell's normal, single-stranded RNA.
The second strand is called the antisense strand because its sequence of nucleotides is the reverse complement of message sense.
The codon 6 detection probe (5'-CTCCTGTGGAGAAGTCTGC-LC Red 640) completely matched the Hb S allele antisense strand.
When linked by complementary base pairing, the two strands that comprise dsDNA are called sense and antisense strands, where the DNA antisense strand is the complementary base pair copy of the DNA sense strand [ILLUSTRATION FOR FIGURE 2 OMITTED].
When applied in functional genomics and drug discovery research, only the contribution of the siRNA antisense strand is desired.