aptamer


Also found in: Medical, Wikipedia.

aptamer

(ˈæptəmə)
n
an artificially created molecule of DNA or RNA
References in periodicals archive ?
[11] proposed a computationally assisted method to study and evaluate aptamer-protein interaction for selecting new aptamer sequences.
brucei cells, the authors demonstrated that the in vivo production of an aptamer containing a single BRC motif leads to an increase in DNA damage sensitivity and inhibition of parasite proliferation.
Quencher-free molecular aptamer beacons (QF-MABs) for detection of ATP.
Comparison of the secondary structures of our isolated aptamers and aptamer A10 obtained by protein SELEX showed similar stem-loop structures which could be responsible for the recognition of PSMA on LNCap cell surface.
First report of the use of a saxitoxin-protein conjugate to develop a DNA aptamer to a small molecule toxin.
Incorporating additional radicals in a structure of nitrogen base allows to expand the spectrum of existing nucleotides, which increases the variation of aptamer libraries and its combinatorial capabilities.
Mahajan continues, Of highest interest is their progress with novel aptamer biosensors.
Located near Houston, close to major medical centres, Base Pair is an aptamer discovery company and its mission is to create novel affinity agents that empower healthcare and protect the planet.
Aptamer Group has signed an agreement with AstraZeneca to explore the potential of using aptamer technology to target the kidney.
Tetracycline binds to the RNA molecule via a so-called RNA aptamer and inhibits ribozyme activity.
The aptamer--peptide probe consisted of 2 conjugated components: an aptamer that could tightly bind to HER2, and substrate peptide that contained a reporter peptide and a tryptic cleavage site before the reporter peptide.
The development of an increased number of G-quadruplex aptamers, which combine the G-quadruplex stiffness and self-assembling versatility with the aptamer high specificity of binding to a variety of molecular targets, allowed the construction of biosensors with increased selectivity and sensitivity.