Arimidex


Also found in: Medical.
Related to Arimidex: tamoxifen

Arimidex

(ˌærɪmɪˈdɛks)
n
(Pharmacology) a trade name for anastrozole
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The independent prognostic and predictive role of PR expression irrespective of ER has been a subject of great controversy as demonstrated by the report from the ATAC (Arimidex, Tamoxifen, Alone or in Combination) adjuvant trial, a large worldwide trial comparing the efficacy of tamoxifen with that of the aromatase inhibitor anastrazole, showing overall that patients with ER+/PR+ tumours had a lower recurrence rate than those with ER+/PR-tumours.3 In the present study the percentage of ER/PR+ patients was 76/120 (63.33%) however the percentage of ER/PR-patients was 20/120 (16.83%) and after that the percentage of ER+ and PR-patients was 16/120 (13.33%).
(NASDAQ: ANIP) has acquired US rights to market AstraZeneca's NDAs ATACAND, ATACAND HCT, ARIMIDEX and CASODEX in a transaction valued at USD 46.5m in cash, royalties and sales-based milestones, the company said.
M2 PHARMA-January 2, 2018-ANI Pharmaceuticals acquires NDAs and US marketing rights for ATACAND, ATACAND HCT, ARIMIDEX, and CASODEX
M2 EQUITYBITES-January 2, 2018-ANI Pharmaceuticals acquires NDAs and US marketing rights for ATACAND, ATACAND HCT, ARIMIDEX, and CASODEX
When cryoablation successfully destroys all of the cancerous cells, there is no need to remove lymph nodes, to have radiation, or to take medications, such as tamoxifen and/or aromatase inhibitors (Arimidex, Aromasin, Femara), that reduce the risk of cancer recurrence."
The global breast cancer therapeutics market report estimates the market size (Revenue USD million - 2013 to 2020) for key market segments based on the drug classes - brand name (chemical name) such as antimetabolites - Gemzar (gemcitabine), aromatase inhibitors - Afinitor (everolimus), Arimidex (anastrozole), Aromasin (exemestane), Femara (leterozole), Ibrance (palbociclib); Her2 Inhibitors - Herceptin (trastuzumab), Kadcyla (ado-trastuzumab emtansine), Perjeta (pertuzumab), Tykerb (lapatinib); Hormone receptors - Fareston, Faslodex, Zoladex; and Mitotic inhibitors - Halaven (eribulin), Ixempra (ixabepilone), Taxotere (docetaxel), and forecasts growth trends (CAGR% - 2016 to 2020).
12, 2013) suggests that another option--anastrozole (Arimidex)--may be more effective.
'I had a total hysterectomy which killed my sex drive and medication, Arimidex - an aromatase inhibitor, gave me prickly heat, hot flushes and nausea.' Previously, before her diagnosis and consequent surgery, Alison and Neil had enjoyed an active sex life, having sex at least three times a week.
The aromatase inhibitor anastrozole (Arimidex) is not recommended by either ASCO or the USPSTF, with data awaited from the ongoing phase III, placebo-controlled British IBIS II (Anastrozole in Preventing Breast Cancer in Postmenopausal Women at Increased Risk of Breast Cancer) study.
And drugs like Arimidex and Herceptin have improved survival rates.
Aromatase inhibitors (Arimidex, Aromasin, or Femara) have fewer side effects and more benefits than tamoxifen.
The company has had several drug development setbacks with experimental depression and ovarian cancer drugs, as well as loss of exclusivity on several key brands, Seroquel IR, Nexium and Arimidex, escalating concerns about long-term strategy and prospects.