Agricultural Research Service scientists and their colleagues have found that global increases in atmospheric carbon dioxide have affected the plant Artemisia annua, a common roadside weed in the United States and the source of artemesinin
, a compound that is used in drugs to treat malaria throughout the world.
9-11) The high burden of malaria deaths in our environment may be due to high levels of parasite resistance to affordable drugs, high cost of artemesinin
based combination drugs and inadequate provision/scarcity of insecticide treated nets.
Extensively and totally drug-resistant tuberculosis (TB) is spreading in the country;  approximately half of all non-albicans candida infections are resistant to fluconazole;  current rates of transmitted resistance to first-line antiretrovirals in HIV are ~5%, yet as antiretroviral roll-out continues, resistance rates are set to rise to 10-17%;  and hopes for the elimination of falciparum malaria are threatened by the risk of spread of artemesinin
resistance from SouthEast Asia.
Some of the useful plant drugs include vinblastine, vincristine, Taxol, Podophyllotoxin, camptothecin, digitoxigenin, gitoxigenin, digoxigenin, tubocurarine, morphine, codeine, aspirin, atropine, Pilocarpine, capsicum, Ellison, curcumin, artemesinin
and ephedrine among others.
He said introduction and expansion of new and effective interventions including the use Rapid Diagnostic Tests (RDTs), Artemesinin
based Combination Therapies (ACTs) for the treatment of falciparum malaria and the promotion of long lasting Insecticide treated bed Nets (LLINs) have brought a revolution in diagnosis, treatment and prevention
, extracted from the herb wormwood, is perhaps our best natural remedy against babesiosis, a common coinfection with Lyme.
The new strain was found in Cambodia by British and American researchers investi-gatina decline in the effectiveness of artemesinin
- the world's main defence against malaria.
These include sesquiterpene lactones as well as an artemesinin
acid analog from T.
Donor funds for the healthcare sector are being channeled towards a multitude of areas including insecticide-treated bed nets for the prevention of malaria, antiretroviral drugs to expand access to antiretroviral therapy in Africa, HIV rapid test kits, laboratory equipment to support the roll out of antiretroviral therapy such as CD4 count and determination of lymphocyte count, artemesinin
combination therapy and other anti-malarial drugs and tuberculosis drugs to support direct observed treatment (DOTS), a TB control strategy.