" Post equitem seclet atra
eura --behind the horseman sits black care."
It is now considered a curable disease, thanks to researchers who demonstrated that arsenic trioxide (ATO) was effective against APL in combination with another drug called all-trans retinoic acid (ATRA
While bcr1 is more sensitive to ATRA
, bcr 3 not only lacks sensitivity but is also associated with a poorer outcome; high TLC and CNS relapse in a number of cases.
decried the failures of bills ranging from an overhaul of the state's venue provisions to a proposal to allow more comparative fault in auto accidents where the injured person wasn't wearing a seatbelt.
However, in the era of differentiation induction therapy with ATRA
and ATO, the risk of lethal hemorrhage secondary to DIC of APL including isolated lung bleeding has been significantly reduced.
affects by serving as an activating ligand of nuclear atRA
receptors (RAR a, b, and g) and peroxisome proliferator-activated receptors (PPAR b/d), which form heterodimers with retinoid X receptors (Mark et al., 2006).
She was continued on an induction course of chemotherapy including ATRA
, dexamethasone, idarubicin, and arsenic trioxide.
To further understand the immunoregulatory mechanism of RA, we explored the role of ATRA
in Tregs in patients with SSc and its possible epigenetic mechanisms.
These governing principles are found in the American Therapeutic Recreation Association (ATRA
) Code of Ethics (COE).
Seagrass Thalassia hemprichii and Sea cucumber Holothuria atra
were collected from Northern corniche of Jeddah and Southern corniche of Jeddah, respectively (Fig.1).
The treatment of acute promyelocytic leukemia (APL) has improved remarkably during the last two decades mainly due to disease-specific drugs, such as all-trans-retinoic acid (ATRA
) and arsenic trioxide (ATO) [1, 2].
(4,5) Usually, APL is sensitive to the differentiating effect of all-iraws retinoic acid (ATRA
) and arsenic trioxide (ATO).