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 (ôk′sə-trŏf′ĭk, -trō′fĭk)
Requiring one or more specific substances for growth and metabolism that the parental organism was able to synthesize on its own. Used with respect to organisms, such as strains of bacteria, algae, or fungi, that can no longer synthesize certain growth factors because of mutational changes.

[Greek auxein, to increase; see auxin + -trophic.]

aux·ot′ro·phy (ôk-sŏt′rə-fē) n.


the inability to synthesize particular growth factors, due to mutational changes
References in periodicals archive ?
L- lysine Production by the Homoserine Auxotrophic Mutant of Corynebacterium glutamicumin Stirrer Fermenter.
The other auxotrophic mutant MRLH-LI, T3, MT8, MTA2, HI6, HA5 and GHI3 produced 27.
Considering the fact, the present study was intended to select suitable maintenance medium for the auxotrophic mutant Micrococcus glutamicus [AB.
Therefore, the auxotrophic mutants which are unable to multiply in the environment were designed.
Of the 12 isolates, 7 were double auxotrophic mutants with G6P and G3P (mean MIC 384 mg/L), 3 were auxotrophic only for G3P (mean MIC 597 mg/L), and 2 were capable of using both substrates and exhibited high-level resistance (MIC >1,024 mg/L).