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A thiazolidinedione drug, C18H19N3O3S, used in its maleate form to treat type 2 diabetes.

[rosi-, origin unknown + -glitazone, thiazolidinedione suff. (alteration of (hyper)gly(cemia) + t(hi)az(olidinedi)one).]


n rosiglitazona
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It's been a long, strange trip for the drug that was approved in 1999 to lower blood sugar in patients with type 2 diabetes and is sold under a number of brands, including Avandia, Avandamet, and Avandaryl, as well as generics.
In November 2007 the FDA extended the warning to cover an increased risk for myocardial infarction, based on "a meta-analysis of 42 clinical studies (mean duration 6 months; 14,237 total patients), most of which compared Avandia to placebo [and] showed Avandia to be associated with an increased risk of myocardial ischemic events such as angina or myocardial infarction.
-- The Food and Drug Administration is lifting restrictions on the use of GlaxoSmithKline Plc's diabetes drug Avandia after determining that its use did not increase the risk of heart attacks.
British drug maker GlaxoSmithKline has agreed to stump up millions of dollars settlement fee, in order to end a raft of lawsuits with eight US states, over improper marketing of its Avandia diabetes drug.
A drug firm are trying to block legal aid for a former DJ who plans to sue over their banned diabetes medication Avandia.
GlaxoSmithKline has agreed to pay $3 billion to the federal government and plead guilty to charges of illegally promoting two antidepressants and withholding key safety information about the diabetes drug Avandia.
The London-based pharmaceutical giant admits in a charging document that it didn't report safety data of its Avandia diabetes drug to regulators, unlawfully marketed Wellbutrin for weight loss and other purposes for which it wasn't approved by U.S.
The actions related to the sales and marketing of anti-depressants Paxil and Wellbutrin, the Medicaid Rebate Program, and the Department of Justice's investigation into the development and marketing of diabetes drug Avandia.
One of the drug prototypes proved capable of reducing disease symptoms in diabetes-prone mice without triggering weight gain or fluid retention, potential side effects of current drugs such as rosiglitazone (Avandia) and pioglitazone (Actos) that can have had fatal consequences in some patients.
The political angst now expressed concerning just one of the drugs, GlaxoSmithKline's Avandia, is dreadfully late--coming a decade after FDA medical reviewer Robert I.
THE UK's largest pharmaceutical company yesterday said the cost of settling legal disputes over controversial diabetes drug Avandia will hit a record pounds 2.2bn.