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Also found in: Medical.


The cytoplasm of an axon.

[Greek axōn + -plasm.]

ax′o·plas′mic (-plăz′mĭk) adj.


of or relating to the axoplasm
References in periodicals archive ?
Mercury damages the nerves in several ways: it interferes with membrane and receptor functions, and neurotransmitter transport and metabolism; it interrupts cytoskeletal proteins, and interferes with axoplasmic flow and signal transduction; it interferes with cell respiration, energy metabolism and others.
Studies have demonstrated that mechanical stress could cause physical alterations in the ONH, such as misalignment of the fenestrate in lamina cribrosa, which may lead to axoplasmic flow obstruction due to its back bowing.
2 Since the optic nerve sheath can be traced as continuation of the subarachnoid space, transmission of effects of raised ICP to the optic nerve causes disruption of the axoplasmic flow, swelling of axons, leakage of water and proteins with resultant optic disc swelling, or papilledema.
It is thought that obstruction of axoplasmic flow causes axons to swell acutely, giving rise to microvesicular changes.
Although the mechanism of drusen formation has not been fully determined, it is believed that congenitally small disc and scleral channels may cause axoplasmic flow stasis and ganglion cell axon death.