B cell

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B cell

n.
Any of a class of lymphocytes that, when activated by a specific antigen and usually also by helper T cells, proliferate and differentiate into antibody-secreting plasma cells or memory cells. In mammals, B cells mature in the bone marrow. Also called B lymphocyte.

[b(ursa-dependent) cell, after the bursa of Fabricius, a gland in birds where the cells mature and the first such tissue found in vertebrates.]

B cell


n.
1. Also called B lymphocyte. a type of white blood cell that circulates in the blood and lymph and produces antibody upon encountering any antigen that has a molecular arrangement complementary to the antibody.
[1970–75]

B cell

Any of the lymphocytes that develop into plasma cells in the presence of a specific antigen, such as a bacterium or virus. The plasma cells then produce antibodies that attack or neutralize the antigen. B cells mature in the bone marrow before being released into the blood. See Note at antibody.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.B cell - a lymphocyte derived from bone marrow that provides humoral immunityB cell - a lymphocyte derived from bone marrow that provides humoral immunity; it recognizes free antigen molecules in solution and matures into plasma cells that secrete immunoglobulin (antibodies) that inactivate the antigens
lymph cell, lymphocyte - an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection
References in periodicals archive ?
It has been reported that estrogen stimulates T-cell-dependent immunity by activating gene expression on T and B lymphocytes. E2 enhances p-ERK 1/2, p-CREB, and p-Akt gene activations via an ER-dependent mechanism.
First by specifically targeting cells expressing CD86, such as monocytes, macrophages, and dendritic cells, while eliminating the undesired stimulation of lymphocytes including resting and activated T and B lymphocytes expressing the IL-10 receptor.
Those [CD8.sup.+] Treg lymphocytes with CTLA-4-mediated suppressor activity that are induced by B lymphocytes and plasmacytoid dendritic cells are effective against an allogeneic response (Figure 5).
In accordance with these results, the above-described outcomes for T and B lymphocytes have been observed in several immunological diseases and have also provided opportunities to selectively modulate specific immune functions by targeting glucose, lipid, and amino acid metabolism [10].
Kaplan, "The long term effects of radiation on T and B lymphocytes in the peripheral blood after regional irradiation," Cancer, vol.
Presentation of the bacterial antigens on the surface of the macrophage then stimulates B lymphocytes specific to the pathogen, and the B cells produce more antibodies to control the infection.
The T4 cells in turn stimulate antibody production by B lymphocytes. Together the activated macrophages, B lymphocytes, and antibodies form granulomas in the affected tissue.