APRIL and BAFF
are both members of the TNF ligand superfamily.
has offered numerous scholarship opportunities for residents of the Baltic States during its five years of operations in the region.
The producers are, and must always be, at the heart of BAFF
The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF
The aim of this study was to determine and compare the serum level of the BAFF
in patients with RA, SLE, and BD and also to correlate its serum level with disease activity indices and severity.
, APRIL and their receptors: structure, function and signaling.
The researchers found that BAFF
interacts with a gene linked to leukemogenesis - the development of leukemia - called c-MYC.
and MyD88 signals promote a lupus like disease independent of T cells.
Soluble variants of BAFF
are the major contributors of its activity, through regulating the survival of B cells (3).
Biyolojik onemi acik olmamasina ragmen YDIY'Ii hastalarda TACI, BAFF
ve bir proliferasyon indukleyici ligand olan APRILin (B hucrelerini aktive eden ve izo tip sinif isaretlenmesini etkilenen) serum duzeylerinin belirgin olarak yukselebildigi bildirilmistir (37).
Palabras clave: Linfocitos B, artritis reumatoide, factor reumatoide, anticuerpos anti-peptidos ciclicos citrulinados (Anti-CCP), BAFF
, anticuerpos anti-CD20.
This is to maintain the status of BAFF
as a foreign invested joint venture.