BRCA


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BRCA

n.
Either of two tumor suppressor genes (BRCA1 or BRCA2) that are associated with an increased risk of developing familial breast and ovarian cancer when inherited in a mutated state.
[br(east) ca(ncer).]
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The test only detects three out of more than 1,000 known BRCA mutations.
FDA Authorizes Test That Reports Three Mutations In BRCA Breast Cancer Genes
The Food and Drug Administration approved AstraZeneca PLC's Lynparza for patients with inherited BRCA gene mutations who have undergone chemotherapy, the FDA said in a statement.
FDA Approves Drug for Women with Breast Cancer Caused by BRCA, the 'Jewish Gene'
Cancer information company ACT Genomics said on Thursday that it has agreed for both somatic and germline genetic testing of BRCA in patients with ovarian cancer with the advanced next generation sequencing (NGS) technology in Singapore and Taiwan in collaboration with AstraZeneca Singapore.
ACT Genomics partners with AstraZeneca for BRCA testing in Singapore and Taiwan
Currently, young women with breast cancer and a BRCA mutation frequently are offered bilateral mastectomy, the authors noted.
POSH study: BRCA mutations did not influence survival
Domchek, executive director of the Basser Center for BRCA at the Abramson Cancer Center of the University of Pennsylvania, and national leader on the OlympiAD trials.
Canada,United States : U.S. FDA Approves LYNPARZA (olaparib) in Germline BRCA-Mutated Metastatic Breast Cancer
The results of 558 of the women, who had the rare triple-negative breast cancer, suggest that those with BRCA mutations have similar survival chances to those without, at five and 10 years after diagnosis.
'Jolie gene' cancer survival rate same as non-carriers
Women diagnosed with early breast cancer who carry a BRCA mutation are often offered double mastectomies soon after their diagnosis or chemotherapy treatment" compared to non-mutation carriers, study co-author Diana Eccles of the University of Southampton said in a statement.
Breast cancer gene does not boost risk of death: study
Mutations in the BRCA gene are associated with several forms of cancer, including breast, ovarian and prostate cancers.
Personalized medicine offers new hope to breast cancer patients
BRCA genes are part of the body's natural defence system and help protect from developing certain types of cancer.
Saliva screening can help cancer diagnosis, say experts
Of those diagnosed with ovarian cancer, only 29 per cent are offered BRCA (BReast CAncer susceptibility) testing, which could inform their treatment and enable them to warn other family members who may also be at risk from the faulty gene.
TAKE GENE TEST, SAVE YOUR LIFE; Mother's appeal to people with family history of cancer
Holtz's interest in my commentary on the role of hysterectomy as part of risk-reducing surgery in BRCA mutation carriers.
Hysterectomy warranted?
To learn how the NEXTflex BRCA1 and BRCA2 Amplicon Panels can improve Illumina or Ion Torrent-based BRCA analysis, visit www.
Bioo Scientific Launches BRCA1/2 Amplicon Panel for Detection of Somatic Mutations in FFPE Samples

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