Histologic evaluation of tissue specimens at 24 and 72 hours revealed destruction of sebaceous glands in the dermis characterized by loss of the definition of the sebocytes, and eosinophilic changes of the basal cell layer
of these glands.
The presence of a continuous basal cell layer
and ciliated cells helps differentiate CMPT from mucinous adenocarcinoma.
WT1 was detected by nuclear staining in the cancer nests proliferating from the basal cell layer
infiltrating the underlying connective tissue and absent to weak staining was found in the basal cell layer
(2) These tumors are thought to arise from either extraosseous remnants of dental lamina or the basal cell layer
of surface epithelium, which is believed to have odontogenic potential.
Its name is taken from the basal cell layer
, as the tumour cells resemble the basal cell layer
of the epidermis.
Immunohistochemical staining confirmed the presence of a discontinuous basal cell layer
in the involved glands, confirming a diagnosis of foamy gland HG PIN.
These cells contain a variety of peptide hormones, lie on the basal cell layer
between secretory cells and are not reliably recognizable by hematoxylin and eosin (HE) examination.
These findings indicate that histogenetically the origin cell of BCC is from the basal cell of epidermis, located at the interfollicular epidermis and infundibulum of the hair follicle distributed along the basal layer, supporting the theories that the origin of BCC arises from the basal cell layer
of the interfollicular epidermis [8, 27], not the ORS and hair follicles [15, 28].
Lymphocytes usually predominate over neutrophils and the epidermis shows a variable degree of spongiosis, reticular degeneration of basal cell layer
, and numerous necrotic keratinocytes.
reported that the hyperreflective deposits were present in the basal cell layer
of the corneal epithelium in both types of diseases, and Wasielica-Poslednik et al.
They are presumed to arise from the remnants of the dental lamina which persist in the oral tissues after the completion of odontogenesis, or from the basal cell layer
of the oral mucosal epithelium.
Oral mucosal melanoma is a rare and ultimately fatal cancer originating from malignant transformation and clonal expansion of neural crest-derived melanocytes residing either in the basal cell layer
of the oral epithelium or in the lamina propria of the oral mucosa.