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 (bā′sə-fĭl, -zə-) also ba·so·phile (-fīl′, -fĭl)
A white blood cell that when activated releases histamine and other substances that are involved in allergic reactions. Basophils are found chiefly in the blood and sites of inflammation and have cytoplasmic granules that are stained with basic dyes.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˈbeɪsəfɪl) or


(Biology) (of cells or cell contents) easily stained by basic dyes
(Biology) a basophil cell, esp a leucocyte
[C19: from Greek; see base1 + -phile]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈbeɪ sə fɪl)

also ba•so•phile

(-ˌfaɪl, -fɪl)

1. a basophilic cell, tissue, organism, or substance.
2. a white blood cell having a two-lobed nucleus and basophilic granules in its cytoplasm.
[1885–90; bas (ic dye) + -o- + -phil]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.


A type of white blood cell readily stained by basic dyes.
Dictionary of Unfamiliar Words by Diagram Group Copyright © 2008 by Diagram Visual Information Limited
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.basophil - a leukocyte with basophilic granules easily stained by basic stains
leucocyte, leukocyte, WBC, white blood cell, white blood corpuscle, white cell, white corpuscle - blood cells that engulf and digest bacteria and fungi; an important part of the body's defense system
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
In 1879 Ehrlich discovered a cell type with dark blue granula in peripheral blood staining experiments with basic dyes [3, 4], which he named "basophilic granulocytes" or "basophils" according to their unique appearance.
To strengthen the body's defense against the attackers, the IgE binds with white blood cell components, specifically the basophils and mast cells.
The percentages of lymphocytes, monocytes, neutrophils, eosinophils, and basophils, and the absolute counts of monocytes, neutrophils, eosinophils, and basophils were similar before and after isotretinoin treatment.
These cells are basophils in the apical region, indicating that they can assume a secretory function, releasing molecules into the spermathecal lumen contributing to spermatozoa maintenance.
A positive result to rocuronium plus sugammadex could be explained by the presence of specific antibodies to rocuronium on the basophils' membrane that quickly activates these cells before sugammadex had any effect on rocuronium molecules.
Mediators released from mast cells and basophils cause clinical signs with vasodilatation, increased capillary permeability and platelet aggregation (2).
The complete blood count (Hemoglobin: 9.4 gm%, total leucocytes count: 18,200/cumm blood, neutrophils: 58%, lymphocytes: 37%, eosionophils: 03%, monocytes: 02% and basophils: Nil) revealed leucocytosis and neutrophilia.
In Table 1 the comparison of blood parameters between TDT patients and control subjects is given which shows that among WBCs, neutrophils have significantly decreased (p<0.05), whereas, lymphocytes and basophils significantly increased (p<0.05) in TDT patients compared with control subjects.
He and his Spanish coinvestigators performed this study to fill an information gap regarding the merits of updosing omalizumab (Xolair), a humanized monoclonal antibody that specifically binds to free immunoglobulin E in the blood and on the surface of selected B lymphocytes, but not on the surface of mast cells, antigen-presenting dendritic cells, or basophils. In the United States, omalizumab is approved at 150 mg or 300 mg subcutaneously administered every 4 weeks for the treatment of CSU not responsive to high-dose antihistamines.