Becker muscular dystrophy

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Related to Becker muscular dystrophy: distal muscular dystrophy

Beck·er muscular dystrophy

A form of muscular dystrophy that begins in late childhood or adolescence, almost exclusively affects males, and is characterized by progressive weakening of the muscles that is similar to but less severe than in Duchenne muscular dystrophy. It is caused by a recessive genetic mutation on the X chromosome that results in insufficiency or abnormality of the protein dystrophin in muscle cells.

[After Peter Emil Becker (1908-2000), German human geneticist .]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Becker muscular dystrophy - a form of muscular dystrophy that sets in in adolescence or adulthood and progresses slowly but will affect all voluntary muscles; characterized by generalized weakness and muscle wasting that affects limb and trunk muscles first; similar to Duchenne's muscular dystrophy but less severe; inheritance is X-linked recessive (carried by females but affecting only males)
dystrophy, muscular dystrophy - any of several hereditary diseases of the muscular system characterized by weakness and wasting of skeletal muscles
References in periodicals archive ?
About Duchenne and Becker muscular dystrophy Duchenne muscular dystrophy is the most common fatal genetic disorder diagnosed in childhood, affecting approximately 1 in every 3,500 live male births (about 20,000 new cases each year worldwide).
The Duchenne Muscular Dystrophy (DMD) and Becker Muscular Dystrophy (BMD) pipeline consists of 84 molecules across all stages of development.
Duchenne and Becker muscular dystrophy prevalence in South Africa and molecular findings in 128 persons affected.
The importance of establishing this diagnosis versus similar and more-common Becker muscular dystrophy is that it has significant treatment implications.
The new short-term clinical trial will move the testing from animals to human patients with Becker muscular dystrophy and examine the effects of acute tadalafil dosing on muscle blood flow during a bout of exercise.
Screening Duchenne and Becker muscular dystrophy patients for deletion in 30 exons of dystrophin gene by three multiplex PCRs.
Parent Project UK was set up by parents and friends of boys with Duchenne and Becker muscular dystrophy and is campaigning for research funding.
The 23-year-old, who suffers from Becker Muscular Dystrophy, has such severe cardiac muscle involvement that he would not have survived unless given the transplant in October 2002.
Abstract: A 40-year-old male with Becker muscular dystrophy and cardiac involvement was stable in New York Heart Association class II for 7 years.
So far, the disorders include female fragile X syndrome (carrier), Fanconi anemia A, 1 bp deletion (carrier), neurofibromatosis type 1 (five cell lines), myotonic dystrophy (two cell lines), Marfan syndrome, [beta]-globin mutation IVS 1-1 (carrier), [beta]-thalassemia, and Becker muscular dystrophy.