Around two dozen patents expired in 2016, including such pharmaceuticals as AstraZeneca PLC's cholesterol drug Crestor (representing $3.4 billion worth of revenue), Daiichi Sankyo's blood pressure drug Benicar
($2.6 billion) and Merck & Co.'s cholesterol drug Zetia ($2.6 billion).
Inhibitors Brilinta Blood Pressure- Benicar
(olmesartan), Atacand v.
These cases are related to olmesartan products (Benicar
HCT, Azor and Tribenzor) and allegations that such products caused sprue-like enteropathy and other severe gastro-intestinal symptoms.
The drugs under the microscope are the Japanese pharma firm's blood-pressure treatments Benicar
HCT, Azor and Tribenzor.
The drug is the generic equivalent of Benicar
Tablets of Daiichi Sankyo Inc.
(6) Combinations have involved migraine-treatment Treximet (combining Imitrex and Naproxen Sodium) and high-blood-pressure medications Azor (Norvasc and Benicar
), Caduet (Norvasc and Lipitor), and Exforge (Norvasc and Diovan).
(branded for Olmesatan) used to treat hypertension; Lixiana in
Expiry of the blockbuster patented drugs such as Gleevec, Namenda, Provigil, Crestor, Benicar
The treatment is made by Japanese firm Daiichi Sankyo and marketed as Benicar
outside the UK.
Olmesartan medoxomil (trade name Benicar
), the prodrug of olmesartan, is an angiotensin II receptor blocker (ARB) that was approved for use in the United States as an antihypertensive medication in 2002.
Paciente Farmacos Dosis Afectacion sistemica tratada 1 Pregabalina (Neurixa) 150 mg Neuralgia diarios 2 Diosmina (Diovenor) 1500 mg Varices 3 Erythropoietin Prostata receptor (EpoR) 4 Rowatinex 3 veces Calculo renal diarios 5 No recuerda Osteoporosis 6 Glucosamine AINES Artrosis degenerativa 7 Levotiroxina 0.5 mg y una Hipotiroidismo (Eutirox), vitamina E, aspirina calcio y Aspirina diaria 8 Olmesartan 20 mg Hipertension y Medoxomil'(Benicar
), diarios vertigo Diosmina (Vedipal) 9 Analgesicos No refiere Fractura de femur 10 Omeprazol, vitaminas Paciente Efectos sobre el hueso 1 Reduce la densidad osea e incrementa el riesgo a la fractura.
Information about some of the studies reviewed by the FDA, including a large observational study of Medicare patients, will be included in the labels of olmesartan products, which include Benicar
HCT, AZO, Tribenzor, and generics.