Benzamide

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Related to Benzamides: Phenothiazines

Ben`zam´ide


n.1.(Chem.) A transparent crystalline substance, C6H5.CO.NH2, obtained by the action of ammonia upon chloride of benzoyl, as also by several other reactions with benzoyl compounds.
References in periodicals archive ?
Ashalatha, Synthesis of some new 5-(2-substituted-1,3-thiazol-5-yl)-2-hydroxy benzamides and their 2-alkoxy derivatives as possible antifungal agents, Eur.
On the basis of chemical structures and enzymatic activities, HDACIs are (Figure 3) (10) chemically classified as hydroxamates (vorinostat, panobinostat, givinostat, quisinostat, abexinostat, belinostat, tefinostat, resminostat, pracinostat), benzamides (entinostat, mocetinostat, chidamide), aliphatic acids (valproic acid), and cyclic peptides (romidepsin).
Based on their chemical structures, HDAC inhibitors include short-chain fatty acids, hydroxamic acids, synthetic benzamides, and cyclic peptides, which exhibit various bioactivities and specificities.
Roberts, "The pharmacological basis of the therapeutic activity of clebopride and related substituted benzamides," Current Therapeutic Research, vol.
Scriba, "Synthesis and pharmacological evaluation of 2-hydroxy methyl benzamides as antiinflammatory and analgesic agents," Acta Poloniae Pharmaceutica, vol.
A range of medications can cause NMS, including phenothiazines, butyrophenones, thioxanthenes, and benzamides as well at the newer atypical antipsychotics.
HDACis can be categorized into six distinct groups: short-chain fatty acids, hydroxamates, cyclic tetrapeptides, benzamides, electrophilic ketones, and miscellaneous [190, 191].
Discovery of substituted benzamides as follicle stimulating hormone receptor allosteric modulators.
Traditional antiemetics like Anticholinergics (Scopolamine, Atropine) Antihistaminics (Dimenhydranates), Phenothiazines (Promethazine), Butyrophenones (Droperidol, Haloperidol) and Benzamides (Metoclopramide) are used for control of PONV.
Table 1: Types of epigenetic drugs: Drugs Class 5-aza-cytidine (azacitidine), Nucleoside DNMTIs 5-aza-2-deoxycytidine (decitabine), 5-fluoro-2-deoxycytidine, Zebularine RG108 Non-Nucleoside DNMTIs MG98 Antisense Oligonucleotides Table 2: HDAC inhibitors: Drugs Class Valproic acid, Aliphatic acids Sodium phenylbutyrate, Pivaloyloxymethyl butyrate, Vorinostat Romidepsin Cyclic peptides Belinostat, Hydroxamic acids Panobinostat Entinostat, Benzamides Mocetinostat
The prokinetic drug class includes substituted benzamides, such as metoclopramide (methoxy-2-chloro-5-procainamide) and bromopride (4-amino-5bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide), which act as dopamine antagonists.