The GM2-gangliosidoses and the elucidation of the beta-hexosaminidase
Urine dermatan sulphate concentrations were elevated in both of them and the gross elevations of plasma beta-hexosaminidase
, arylsulphatase A and alphamannosidase were consistent with a diagnosis of ML II/III.
. We measured the concentration of beta-hexosaminidase
in both the supernatant and the cells.
Naringenin has been shown, along with other flavanones such as hesperetin and ponciretin, to strongly inhibit IgE-induced beta-hexosaminidase
release from RBL-2H3 cells.
subunit alpha isoform 1 3.
The researchers also reported that brain cells in the treated mice exhibited normalized levels of the glycosaminoglycans and the lysosomal enzyme beta-hexosaminidase
. With continued treatment through hematopoietic stem cell gene therapy, normalized levels persisted until the end of a five-month observation period, researchers said.
Several tests have recently been proposed, such as mitochondrial acetaldehyde adducts, beta-hexosaminidase
or phosphatidylethanol (PEth), with promising results.
Effects of the cannabimimetic fatty acid derivatives 2-arachidonoylglycerol, anandamide, palmitoylethanolamide and methanandamide upon IgE-dependent antigen-induced beta-hexosaminidase
, serotonin and TNF alpha release from rat RBL-2H3 basophilic leukaemia cells.
Several other markers with considerable potential for measuring recent alcohol intake include beta-hexosaminidase
, acetaldehyde adducts and the urinary ratio of serotonin metabolites, 5-hydroxytryptophol and 5-hydroxyindoleacetic acid.
Current status of carbohydrate-deficient transferrin, total serum sialic acid, sialic acid index of apolipoprotein J and serum beta-hexosaminidase
as markers for alcohol consumption.
IgE-mediated release of leukotriene C4, chondroitin sulfate E proteoglycan, beta-hexosaminidase
, and histamine from cultured bone marrow-derived mouse mast cells.