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Noun1.Bextra - a Cox-2 inhibitor (trade name Bextra) that relieves pain and inflammation without harming the digestive tractBextra - a Cox-2 inhibitor (trade name Bextra) that relieves pain and inflammation without harming the digestive tract
Cox-2 inhibitor - an anti-inflammatory drug that fights pain and blocks Cox-2 activity without impeding the activity of Cox-1; increases the risk of heart attacks; "Cox-2 inhibitors reduce the symptoms of arthritis without endangering the stomach and kidneys"
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References in periodicals archive ?
Bextra, which is another cox 2 inhibitor, was taken off from many European and U.S.
ABCDEFGHIJKLMNOPQRSTUVWXYZ BEXTRA LETTER LINE: Call 1550 999 064 ([euro]0.95c/min) for up to five extra letters.
One can't help but notice a couple of ironies here: First, in 2009, Pfizer settled government charges that it unlawfully marketed Bextra, and the case also involved charges of off-label promotion for Lyrica[R] (indications other than the newly approved one appear to have been involved).
While two others in its class of drugs, Vioxx and Bextra, were removed from the market in 2004 and 2005, respectively, celecoxib (Celebrex) remains available, but with a black box warning that it carries the risk of heart attack and stroke.
Ten years ago:The blockbuster painkiller Bextra was taken off the market, and the FDA said all similar prescription drugs should strongly warn about possible risk of heart attacks and strokes.
The company's investors had claimed that Pfizer made misleading statements connected to a government investigation of Pfizer's off-label marketing practices of Bextra and other drugs, an investigation that eventually led to a $2.3 billion settlement in 2009.
These include rofecoxib (Vioxx), valdecoxib (Bextra), and sibutramine (Meridia).
was flying high on the booming sales of its blockbuster arthritis drugs Celebrex and Bextra. But things began crashing down when an independent study published in 2004 showed that patients who took the drugs had a high risk of blood clots and other cardiovascular problems.
That record is now held by Pfizer Inc, which paid a $1.3 billion criminal fine in 2009 for marketing fraud related to its Bextra pain medicine.
(NYSE: PFE) struck in 2009 to settle an investigation of improper drug marketing related to its Bextra painkiller.
SAVE pounds 3.33 SAVE pounds 5 (no SAVE pounds 4.50 BExtra Special Malbec (70cl), was pounds 6.48, now pounds 5.