bisphosphonate

(redirected from Bisphosphonates)
Also found in: Medical.

bis·phos·pho·nate

 (bĭs′fŏs′fə-nāt′)
n.
Any of a class of drugs that decrease bone resorption by inhibiting osteoclasts, used in the treatment of osteoporosis, Paget's disease, bone metastases, and other conditions. Also called diphosphonate.

[bis- + phosphon(ic acid), phosphorous acid (from phosphonium) + -ate.]

bisphosphonate

(ˌbɪsˈfɒsfəneɪt)
n
(Pharmacology) any drug of a class that inhibits the resorption of bone; used in treating certain bone disorders, esp osteoporosis
Translations

bisphosphonate

n bisfosfonato
References in periodicals archive ?
CLINICAL QUESTION: Do postmenopausal women who have osteoporosis and are using bisphosphonates have less alveolar bone loss than postmenopausal women with osteoporosis not using bisphosphonates?
Objective: To study the protective effect of Bisphosphonates (Pamidronate) in patients of primary osteoporosis in Pakistani setup.
It has been known for some time that prolonged use of bisphosphonates can put people at risk for atypical femoral fracture (AFF), a break in the femur (thigh bone) that can occur with little or no trauma.
LAS VEGAS -- Bisphosphonates may slow the onset and progression of osteoarthritis, according to data from the National Institutes of Health--sponsored Osteoarthritis Initiative.
THE MOST IMPORTANT recommendation in this updated ACP guideline is for clinicians to offer bisphosphonates or denosumab to women with osteoporosis.
Bisphosphonates are one of the most widely prescribed drugs for the treatment of osteoporosis and the reduction of fracture risk.
"The most important take-home message from the recent guidelines on bisphosphonate therapy is that, for women treated with bisphosphonates, a 'drug holiday'--that is, stopping the medication for two to three years--should be considered following five years of oral or three years of intravenous bisphosphonate use, depending on the patient's response to treatment," explains Jason Baker, MD, an endocrinologist at Weill Cornell Medicine and New York-Presbyterian Hospital.
Objective: To evaluate the oncologists thoughts about the positive and adverse effects of bisphosphonates, drug holiday and the awareness about BRONJ.
A An association has been found between bisphosphonates and "atypical" fractures in the femur (thighbone).
Objective: This meta-analysis was conducted to investigate the efficacy of bisphosphonates for preventing recurrent hip fracture and reducing the mortality of elderly patient with hip fracture.
Given the effective metal-complexing behavior of bisphosphonates, some synergistic effects of bisphosphonates and metal complexes maybe expected.