A fungal pathogen isolated postmortem from brain and lung tissue was initially identified as Blastomyces
dermatitidis on the basis of serologic and histopathologic findings, but its features in culture were atypical (3).
Additional negative tests included serum galactomannan and [beta]-d-glucan, serology for Cryptococcus, Histoplasma, Blastomyces
and Coccidioides, CMV PCR, EBV PCR as well as fungal, mycobacterial and bacterial blood cultures.
MVista Antigen Detection: Histoplasma, Coccidioides, and Blastomyces
Quantitative EIA Other Antigen Detection: Aspergillus Galactomannan, B-D Glucan Antibody Detection: MVista Histoplasma IgG IgM, MVista Coccidioides IgG IgM, Blastomyces
, and Aspergillus
2) Although these methods have the advantage of being non-invasive, but enclose several limitations, including (i) marked intra-patients variation in results; (ii) long time for positive results (up to six weeks are required after exposure for antibody production); (iii) potential cross-reactivity with antibodies produced by other fungi such as Blastomyces
dermatitidis causes this relatively rare fungal disease.
Examples of such fungi include Blastomyces
, Coccidioides, and Histoplasma.
posadasii belong to the Dikaryomycota class, of the Onygenaceae family (to which other dimorphic fungi such as Paracoccidioides brasiliensis, Histoplasma capsulatum and Blastomyces
Common fungi causing conjunctivitis are: Candida albicans, Candida parapsilosis, Candida tropicalis, Paracoccidioides brasiliensis, Coccidioides immitis, Blastomyces
dermatitidis, Rhinosporidium seeberi, Sporothrix schenckii, etc.
Results of investigations for human immunodeficiency virus, syphilis, Lyme disease, human herpesvirus 6 and 7, and species of Babesia, Toxoplasma, Histoplasma, Cryptococcus, Blastomyces
, and Brucella were negative.
The Fungitell assay (Associates of Cape Cod, East Falmouth, Massachusetts) detects 1,3-[beta]-D-glucan (BG), a component of many medically important fungi, such as Candida spp, Aspergillus spp, Fusarium spp, Pneumocystis jiroveci, Coccidioides immitis, Histoplasma capsulatum, and Blastomyces
In vitro activities of voriconazole, itraconazole, and amphotericin B against Blastomyces
dermatitidis, Coccidioides immitis, and Histoplasma capsulatum.
Se ha demostrado que la pared de las celulas levaduriformes en hongos dimorficos como Blastomyces
dermatitidis, Histoplasma capsulatum y P brasiliensis contienen predominantemente [alfa]-glucano y solamente pequenas cantidades de [beta]-glucano, mientras que el [beta]-glucano es abundante en la fase micelial (19).