Bohr effect


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Bohr effect

n.
An effect by which an increase of carbon dioxide in the blood and a decrease in pH results in a reduction of the affinity of hemoglobin for oxygen.

[After Christian Bohr (1855-1911), Danish physiologist.]
References in periodicals archive ?
However, suboptimal carbon dioxide levels may result in constriction of smooth muscle, reduced oxygen release (via the Bohr effect) and increased sympathetic nervous system activity.
Ueda noted that if HbS behaved as predicted by it's abnormal Bohr effect, even a mild, transient acidosis would be dangerous for a child in ACS because the right shifted hemoglobin dissociation curve causes a large release of oxygen from red cells, an event that would cause further RBC sickling.5 Barnard and colleagues noted that this cascade of events increased the risk of further erythrocyte sickling and would cause further vaso-occlusion, and worsened shunt physiology.
Oxygen affinity and Bohr effect. In all three species, there was no significant change in hemocyanin oxygen affinity at Day 12 or Day 25+ of hypoxia exposure compared to controls held for the same time in normoxia, as determined by complete overlap of 95% confidence intervals around the regression of log [P.sub.50] vs.