Using bone samples from people undergoing hip replacement surgery, researchers from the University of Southampton were able to show that the drug - a protein that activates a molecular pathway called the 'Wnt' pathway - causes stem cells found within bones to divide and to turn into more bone cells
ViviGen is the outcome of a four-year research and development process, during which LifeNet Health created new techniques for tissue recovery, preparation, preservation and packaging in order to maintain viability in sensitive bone cells
Beneath it is the inner shell of hard bone, composed of columns of bone cells
In the present study, the objective was to synthesize a bioactive and biocompatible material that is able to speed up the proliferation and differentiation of bone cells
in addition to having the advantages of other bioactive materials.
Among specific topics are bone modeling and remodeling, skeletal hard tissue biomechanics, skeletal growth and development, hormonal effects on bone cells
, and pharmaceutical treatments of osteoporosis.
The study is novel in that the researchers directly delivered bone-producing instructions (using piece of DNA that encodes for a platelet-derived growth factor called PDGF-B) to existing bone cells
in vivo, allowing those cells to produce the proteins that led to more bone production.
The authors concluded that the CaP/gel/Ti implants fabricated using their urease process not only enhanced the proliferation of stem cells and differentiation of bone cells
, but also the bone bonding ability of the implants.
Broken bones and joint replacements someday may heal faster, thanks to an unusual coating for medical implants under development, reports the journal Ceramics International, as researchers have found that bone cells
grow and reproduce faster on a textured surface than they do on a smooth one--and they grow best when they can cling to a microscopic shag carpet made of tiny metal oxide wires.
The findings confirmed previous work showing that tributyltin affects the regulation of body fat production and reprograms certain stem cells to become fat cells rather than bone cells
Libera has been awarded a patent titled “Surfaces Differentially Adhesive to Bacteria & Eukaryotic Cells” for a technology that repels bacteria and promotes the growth of bone cells
around an implant.
Stem cells are cells that can grow into any type of cell in the body--even muscle or bone cells
Artificial grafts offer an easier and less risky process, providing an artificial scaffold on which bone cells