Louseborne relapsing fever (LBRF), which is caused by the spirochete Borrelia recurrentis
, once had a cosmopolitan distribution but is now endemic only to countries in the Horn of Africa (Ethiopia, Sudan, South Sudan, and Somalia) (1,2).
The Lyme panel tests for four different genes of Borrelia burgdorferi and several common Lyme disease co-infections: Babesia microti, Babesia divergens, Babesia duncani, Bartonella bacilliformis, Bartonella henselae, Bartonella quintanta, Borrelia miyamotoi, Borrelia recurrentis
, Ehrlichia chaffensis and Anaplasma phagocytophilum.
Robert et al., "The genome of Borrelia recurrentis
, the agent of deadly louse-borne relapsing fever, is a degraded subset of tick-borne Borrelia duttonii" PLoS Genetics, vol.
Presentan una moderada especificidad (72-89%), debido a su falta de estandarizacion responsable de variaciones interlaboratorios y a la existencia de reacciones cruzadas con otros microorganismos (Treponema pallidum, Borrelia recurrentis
, Helicobacter pylori, Ehrlichia, Babesia), enfermedades autoinmunes (lupus eritematoso sistemico) y sindromes virales (virus Epstein-Barr) (12).
So too are the genomes of the bacterial pathogens that the body louse transmits to its human hosts: Rickettsia prowazekii (which causes epidemic typhus), Borrelia recurrentis
(the agent of relapsing fever) and Bartonella quintana (which causes trench fever).
Louse-borne relapsing fever (Borrelia recurrentis
) diagnosed in 15 refugees from northeast Africa: epidemiology and preventive control measures, Bavaria, Germany, July to October 2015.
Our panel includes ten such organisms: Anaplasma phagocytohilium, Babesia divergens, Bartonella bacilliformis, Ehrlichia chaffeensis, Borrelia recurrentis
, Borrelia miyamotoi, Babesia duncani, Bartonella henselae, Babesia microti, and Bartonella quintana.
The causative agent is the spirochete bacterium Borrelia recurrentis
. In nature, the only relevant vector is the body louse, which feeds only on humans; no other reservoir for this infection is known (1,3).