These include generic names cetirizine, levocetirizine, chlorpheniramine, diphenhydramine, ketotifen and brompheniramine
(The sedating antihistamines prescribed included hydroxyzine, diphenhydramine, chlorphenirarnine, brompheniramine
, and cyproheptadine; nonsedating antihistamines include cetirizine, desloratadine, levoce-tirizine, loratadine, and fexofenadine.)
First generation H antihistamines (e.g., diphenhydramine, chlorpheniramine, brompheniramine
) are usually poorly tolerated by older adults because they are highly anticholinergic.
Children's Dimetapp (CDT) contains brompheniramine
maleate, phenylephrine hydrogen chloride, and dextromethorphan hydrogen bromide as active ingredients.
Moreover, the chiral ILs were applied for the enantiomer separation of eight racemic drugs (chlorpheniramine, brompheniramine
, pheniramine, Tropicamide, Bifonazole, promethazine, warfarin, and liarozole) by capillary electrophoresis .
The paediatric syrup medicines which were chosen for this study were the antihistamines: Claritin[R] (Loratadine--Batch number: 53425, Schering-Plough, Vila Olimpia, Brazil) and Dimetapp Elixir[R] (Brompheniramine
and Pseudoephedrine--Batch number: 801, Wyeth, Sao Paulo, Brazil).
Generic name Trade name (a) Labeler/manufacturer Brompheniramine
Dimetane Allergy Whitehall-Robins Extentabs Aspirin-delayed Entrophen ECT 975 mg Pendopharm, Division release (Canada) of/de Pharmascience Inc (Canada) Enteric Coated A.SA Pendopharm, (Canada) Pharmascience (Canada) Bisacodyl Dulcolax Bisacodyl Boehringer Ingelheim Laxative Tablets Dulcoiax ECT 5 mg Boehringer Ingelheim (Canada) Canada Ltd.
A Allergists generally recommend that older adults avoid first-generation antihistamines such as diphenhydramine (Benadryl), chlorpheniramine (Chlor-Trimeton), dimenhydrinate (Dramamine), brompheniramine
(Dimetapp and others), clemastine fumarate (Tavist, Allerhist), and dexbrompheniramine (Drixoral).
The companies added Lodrane D is an immediate release formulation of brompheniramine
maleate and pseudoephedrine HCl, an effective, low-sedating antihistamine combined with a decongestant.
* Take a sustained-release first-generation antihistamine like brompheniramine
(Lodrane 24) or clemastine (Tavist Allergy 12-Hour Relief Tablets), In recent clinical trials, their effectiveness against sneezing, runny nose, and possibly cough has been impressive.
These include brompheniramine
(Dimetapp), chlorpheniramine (Allergex), and diphen-hydramine (Benalyn).