Creutzfeldt-Jakob disease(redirected from Bubble and Hole Disease)
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n. Abbr. CJD
A fatal degenerative disease of the brain, caused by a prion and marked by progressive dementia and gradual loss of muscle control. Also called Jakob-Creutzfeldt disease.
[After Hans G. Creutzfeld (1883-1964) and Alfons M., Jakob (1884-1931), German psychiatrists.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
Creutzfeldt-Jakob disease(ˈkrɔɪtsfɛlt ˈjɑːkɒp)
(Pathology) pathol a fatal slow-developing disease that affects the central nervous system, characterized by mental deterioration and loss of coordination of the limbs. It is thought to be caused by an abnormal prion protein in the brain
[C20: named after Hans G. Creutzfeldt (1885–1964) and Alfons Jakob (1884–1931), German physicians]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
Creutz′feldt-Ja′kob disease`(ˈkrɔɪts fɛltˈyɑ kɔp)
a fatal degenerative disease of the human brain, thought to be caused by an abnormal, infectious form of cellular prion protein.
[1965–70; after German physicians Hans German. Creutzfeldt (1885–1964) and Alfons Jakob (1884–1931)]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
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|Noun||1.||Creutzfeldt-Jakob disease - rare (usually fatal) brain disease (usually in middle age) caused by an unidentified slow virus; characterized by progressive dementia and gradual loss of muscle control|
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n no pl → Creutzfeldt-Jakob-Krankheit f
Collins German Dictionary – Complete and Unabridged 7th Edition 2005. © William Collins Sons & Co. Ltd. 1980 © HarperCollins Publishers 1991, 1997, 1999, 2004, 2005, 2007