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A potent, long-acting anesthetic, C18H28N2, used for regional anesthesia in its hydrochloride form.

[bu(tyl) + pi(peridine) + (no)vacaine (popular rendering of the trademark Novocain, influenced by cocaine).]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Medicine) a local anaesthetic of long duration, used for nerve blocks
[C20: perhaps from bu(tyl) + pi(pecoloxylidide), the drug's chemical components + -vacaine, from (No)vocaine]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
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Spinal anaesthesia with hyperbaric Bupivacaine Hydrochloride is popular for longer procedures due to its prolonged duration.
In one recent retrospective study, abdominal incision infiltration with liposomal bupivacaine was associated with less opioid use (with no change in pain scores), compared with bupivacaine hydrochloride after laparotomy for gynecologic malignancies (Obstet Gynecol.
Group BD: received epidural study solution of 38 ml of 0.25% bupivacaine hydrochloride + 1 ml of 100 [micro]g dexmedetomidine + 1 ml of normal saline.
Therefore, stock solutions of mepivacaine 1% and bupivacaine 0.25% were prepared from mepivacaine hydrochloride 2% W/V [Mepicain 2% (Monico SPA)] and bupivacaine hydrochloride: 5 mg/mL (0.5% W/V) [Marcaina 5 mg/mL (Astra Zeneca)], respectively, by diluting 1:1 the commercially available solutions with the relevant vehicles.
The patients were divided in to three groups according to type of anesthesia used; group I was those patients who had local anesthesia, that is 20 cc bupivacaine hydrochloride 0.5% with adrenaline and lingocaine hydrochloride 2% were injected around the anal skin, and intersphincter plane and sedation 2 cc fentanyle and 2 cc dormecium were given intravenously.
Patients with a unilateral inguinal hernia undergoing open hernioplasty with mesh placement will be treated in one of two arms per study: three 100 mg XaraColl matrices for a total dose of 300 mg of bupivacaine hydrochloride, or three placebo matrices.
To administer the treatment, the doctor used low dose X-ray to guide an injection of bupivacaine hydrochloride, a commonly used local anesthetic, into a nerve bundle called the stellate ganglion, located in the neck near the "voice box."
The local anesthetic commonly used is bupivacaine hydrochloride, which has a rapid onset; anesthesia occurs within 4-17 minutes of administration.
Study participants were randomly assigned to two groups once they had reached full dilatation while receiving standardized epidural infusions of bupivacaine hydrochloride (Marcaine) and fentanyl designed to minimize the motor block while maintaining comfort.
M2 EQUITYBITES-October 21, 2011-Sagent Pharmaceuticals Inc secures US FDA approval of bupivacaine hydrochloride injection(C)2011 M2 COMMUNICATIONS http://www.m2.com