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An abnormal increase in the number of cells in a tissue or organ, with consequent enlargement of the part or organ.

hy′per·plas′tic (-plăs′tĭk) adj.


(Pathology) enlargement of a bodily organ or part resulting from an increase in the total number of cells. Compare hypertrophy
hyperplastic adj


(ˌhaɪ pərˈpleɪ ʒə, -ʒi ə, -zi ə)

1. abnormal multiplication of cells.
2. enlargement of a part due to an abnormal numerical increase of its cells.
hy`per•plas′tic (-ˈplæs tɪk) adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.hyperplasia - abnormal increase in number of cells
dysplasia - abnormal development (of organs or cells) or an abnormal structure resulting from such growth
benign prostatic hyperplasia, BPH - enlarged prostate; appears to be part of the natural aging process


n. hiperplasia, proliferación excesiva de células normales en un tejido.


n hiperplasia; benign prostatic— hiperplasia prostática benigna; congenital adrenal — hiperplasia suprarrenal congénita
References in periodicals archive ?
The role of C-cell hyperplasia (CCH) in the development of familial medullary thyroid carcinoma (MTC) has been studied extensively, and the preneoplastic nature of CCH in this setting is well established.
The concomitant occurrence of autoimmune thyroid diseases [Hashimoto's thyroiditis (HT) and Graves' disease], and thyroid neuroendocrine tumours and other neoplasms (C-cell hyperplasia, medullary thyroid cancer, papillary thyroid cancer and neurofibroma) with NF1 has been reported in previous studies (4,9-13).
The fact that the pyramidal lobe as well as the isthmus of the thyroid gland does not contain C-cells was used by a group of German authors for an operation named 'Isthmus-preserving total bilobectomy' in patients with C-cell hyperplasia. (26)
It is not uncommon, especially in inherited cases, to see a background of C-cell hyperplasia.
One of the target organs to toxins and drugs is the thyroid gland, which dysfunction is manifested as hypothyroidism, hyperthyroidism, c-cell hyperplasia (7,8).