CD4

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Related to CD4 antigen: CD4+ cell

CD4

 (sē′dē-fôr′)
n.
A glycoprotein that is found on the surface of T cells, especially helper T cells, and functions as a receptor in activation of the cells. In humans, HIV gains entry to helper T cells by binding to the CD4 receptor.

[c(luster of) d(ifferentiation antigen) 4.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

CD4


n.
a protein on the surface of T cells and other cells, functioning as a receptor for the AIDS virus antigen.
[1980–85; c(luster of) d(ifferentiation) 4]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.CD4 - a glycoprotein that is found primarily on the surface of helper T cells; "CD4 is a receptor for HIV in humans"
glycoprotein - a conjugated protein having a carbohydrate component
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
The study of the ability of individual H and L chains to inhibit the binding of moAbs to CD4 antigen or moAb2 has shown that only the L chain 16D7 of moAb can specifically inhibit these interactions [4].
In summary, a partially purified MAF derivative (MAFds) inhibited the replication of the human immunodeficiency virus (HIV) by specific gp 120 binding and interfering with syncytium formation between the viral gp120 envelope protein and the lymphocyte CD4 antigen. Thus, in pure form, it will qualify at a clinical level as a microbicide or as a microbistatic agent, similar in its chemical properties to HIV-inhibitory products derived from some other marine invertebrates [13].