tumour necrosis factor

(redirected from CD40LG)
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Noun1.tumour necrosis factor - a proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheumatoid arthritis)
cytokine - any of various protein molecules secreted by cells of the immune system that serve to regulate the immune system
References in periodicals archive ?
miR 146a-5p was also predicted as a miRNA for CD40LG, which had a borderline increase in protein (FDR 0.
Varios estudios han revelado que el tratamiento de celulas T normales con 5-azaC (inhibidor de metilacion de DNA 5-azacytidina) induce la sobre expresion de genes sensibles a la metilacion, como TNFSF7 (CD70), PRF1 (perforina) y CD40LG (CD40L), mismos que se encuentras hipometilados en celulas T de pacientes con lupus.