CD8


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CD8

 (sē′dē-āt′)
n.
A glycoprotein that is found on the surface of certain T cells, especially cytotoxic T lymphocytes, and that functions to bind the T cell to molecules on the surface of the target cell that is to be killed.

[c(luster of) d(ifferentiation antigen) 8.]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.CD8 - a membrane glycoprotein that is found primarily on the surface of cytotoxic T cells
glycoprotein - a conjugated protein having a carbohydrate component
References in periodicals archive ?
The report provides an overview of the cell surface marker testing in Europe (France, Germany, Italy, Spain, UK), including 5-year forecasts for CD4, CD8, CD34 and other markers by country.
We know from previous studies in non-human primates that CD8 T cells played a crucial role in protecting animals that had been vaccinated with this NIAID/GSK vaccine and then exposed to otherwise lethal amounts of Ebola virus," said Julie E.
Professor Lalvani said that the immune system produces these CD8 T cells in response to usual seasonal flu.
In addition to the conventional endothelial markers, the lymphatic endothelium shows strong immunoreactivity for D2-40 and is negative for CD21 and CD8.
Each cultured PB and SF sample was aliquoted and stained in three different tubes (100 [micro]L/tube) following an intracytoplasmatic permeabilization and staining protocol in order to analyze the intracellular expression of IL-17 within the CD8 T-cell subset.
Almeida M, Cordero M, Almeida J, Lopez A, Orfao A: CD38 on peripheral blood cells: The value of measuring CD38 expression on CD8 T-cells in patients receiving highly active anti-retroviral therapy.
Soluble markers that have been studied in HIV include IgA, IgG, neopterin, 2 microglobulin, soluble CD8, soluble CD25 and soluble TNF and IL-2 receptors [4,29-32].
A pilot study on observations on CD4 and CD8 counts in healthy HIV seronegative individuals.
Echinacea and Astragalus primarily stimulated CD8 T cells, and to a lesser extent CD4 T cells.
Investigations with CD4 and CD8 antibodies were performed each with one donor in nearly the same manner.
Aurelian notes that both dl5-29 and Delta PK hike production of a CD8 T cell protein called interferon gamma.
Results: CD4 and CD8 counts and CD4:CD8 ratios were normal in all eight patients, in contrast to the suppressor cell proliferation and low helper-suppressor ratios that have been previously reported in other patients with B-cell chronic lymphocytic leukemia.