CD8 cell

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Related to CD8+ cell: Cytotoxic T lymphocytes
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Noun1.CD8 cell - T cell with CD8 receptor that recognizes antigens on the surface of a virus-infected cell and binds to the infected cell and kill it
T cell, T lymphocyte - a small lymphocyte developed in the thymus; it orchestrates the immune system's response to infected or malignant cells
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References in periodicals archive ?
CD8B molecule contributes to CD8+ cell development (Bosselut et al., 2000), and CD81 protein is involved in activation, proliferation and differentiation of T cells (Levy et al., 1998), indicating that the 2 DEGs (CD8B down-regulation and CD81 up-regulation) may be associated with blood T lymphocyte subsets.
In HLA-mating sibling and unrelated transplant settings, Reshef et al .[14] observed the relationship of higher CD8+ cell doses with improved survival.
In the comparison of the IBS-D and control groups, serotonin-positive cells; IELs; CD20+ cell counts in terminal ileal and rectal biopsy specimens; and CD3+, CD4+, and CD8+ cell counts in terminal ileal biopsy specimens showed no statistically significant difference (p>0.05) (Table 2).
This finding recapitulates the data we reported recently for the global STAT4 deletion in obese C57Bl/6J mice, where STAT4deficiency discriminately reduced the CD8+ cell numbers and migratory potential [17].
FACS analysis of intracellular IL-4 production was performed in combination with CD4+ and CD8+ cell surface marker expression in peripheral blood lymphocytes.
Researchers measured CD4+ cell numbers, CD8+ cell numbers, and NK cell activity in all patients.
Age-related immune dysfunction in health and in human immunodeficiency virus (HIV) disease: association of age and HIV infection with naive CD8+ cell depletion, reduced expression of CD28 on CD8+ cells, and reduced thymic volumes.
In this study CD4+ and CD8+ cell counts were compared in three different forms of tuberculosis.
CD8+ cell anti-HIV activity correlates with the clinical state of the infected individual.
We followed patients for 8 years, and such long period of time enabled us to observe continuous increase in CD4+ T-cell and decrease in CD8+ cell activation.
In our study of human VSBV-1 infections, we did not observe this effect; rather, CD4+ and CD8+ cells were equally distributed around blood vessels and in the brain parenchyma.