CD8 cell


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Noun1.CD8 cell - T cell with CD8 receptor that recognizes antigens on the surface of a virus-infected cell and binds to the infected cell and kill it
T cell, T lymphocyte - a small lymphocyte developed in the thymus; it orchestrates the immune system's response to infected or malignant cells
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References in periodicals archive ?
High graft CD8 cell dose predicts improved survival and enables better donor selection in allogeneic stem-cell transplantation with reduced-intensity conditioning.
DM cells from invasive tumor margins showed increased CD8 cell density PD-L1 expression.
That may have been an error, because it turns out that the CD8 cell's function crashes during MS attacks.
Laboratory data used for comparison between the two groups were CD4 and CD8 cell counts, hemoglobin levels, and absolute number of lymphocytes.
(14) To underpin this proposal, he cites two studies-an ex vivo analysis and in vitro model of CD8 cells showing close correlation between activation level and CD8 cell differentiation (as an indicator of "replicative senescence") (15) and a comparison of CD4- and CD8-cell markers in 20 fast progressors and 40 slow progressors linking "a shift in the T-cell population toward an aged conformation" in people with more advanced infection.
Multivitamins also led to significantly higher CD4 and CD8 cell counts, significantly lower viral loads, significantly fewer oral and gastrointestinal manifestations, and significantly reduced RR of progression to stage 3 or greater disease (RR 0.72) and to stage 4 disease (RR 0.50) in the pregnant women, the study investigators reported (N.
Bertoletti, "Quantity and quality of virus-specific CD8 cell response: relevance to the design of a therapeutic vaccine for chronic HBV infection," Molecular Immunology, vol.
It was recognised from the earliest reports of AIDS that the CD4 cell depletion was also accompanied by a CD8 cell increase (with a resulting inversion of the normal CD4/CD8 ratio).
CD8 cell counts increased by an average of 181 cells/mm3 in the patients smoking marijuana, by 60 cells/mm3 in those receiving dronabinol, and by 18 cells/mm3 in those receiving placebo.
This study shows that the frequency of CD4+ T cells in brucellosis patients is lower than that of healthy controls, while the CD8 cell frequency is higher than that of controls, and the ratio of CD4/CD8 is lower than the control group, which shows that there is immunologic dysfunction of the T lymphocyte in patients with brucellosis.
SAN FRANCISCO -- A randomized trial of smoked marijuana and dronabinol in HIV-positive patients revealed significant weight gain in both experimental groups and significant increases in CD8 cell counts in the marijuana group.
That's the indirect measure--it's not the CD4 cell that's directly impacting viral load, it's the CD8 cell. What we're saying is you need the CD4s to get the CD8s to work.