reh

(redirected from CES1)
Also found in: Medical, Financial.

reh

(reɪ)
n
a salty surface crust found on the soil in parts of India
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
This enzyme exhibits a 60-fold higher hydrolytic efficiency against irinotecan than CES1, another human carboxylesterase isozyme [1], and the ability of colorectal tumors to hydrolyze irinotecan correlates with their expression of CES2, but not CES1 [2].
For MA chemicals, the target genes NQO1, HMOX1 and CES1 (Roberts et al., 2007) were even present on the input transcripts level.
[4] Human genes: APOE, apolipoprotein E; SLCO1B1, solute carrier organic anion transporter family member 1B1; LPA, lipoprotein(a); SORTI, sortilin 1; ABCB1, ATP binding cassette subfamily B member 1; ABCG2, ATP binding cassette subfamily G member 2; HMGCR, 3-hydroxy-3-methylglutaryl-CoA reductase; CELSR2, cadherin EGF LAG sevenpass G-type receptor 2; PSRC1, proline and serine rich coiled-coil 1; KIF6, kinesin family member 6; CYP2C19, cytochrome P450 family 2 subfamily C member 19; P2RY12, purinergic receptor; CYP2C9, cytochrome P450 family 2 subfamily C member 9; CES1, carboxylesterase 1; UGT2B7, UDP glucuronosyltransferase family 2 member B7; VKORC1, vitamin K epoxide reductase complex subunit 1.
Genetic variabilities which may interfere with clopidogrel variable platelets reactivity include the polymorphisms of the CYP2C19 [19], the CYP3A4/5 [20], the CYP2C9 [21], the ATPBinding Cassette Subfamily B Member 1 (ABCB1) [22], the Paraoxonase-1 (PON1), the Carboxyl Esterase 1 (CES1) [23], and the genetic polymorphism of the P2Y12 receptors [24].
In both [Ogg1.sup.-/-] and [Ogg1.sup.+/+] PB-treated mice livers, comparable significant overexpression of CAR and PXR downstream enzymes involved in xenobiotic metabolism including CYP2B10, CYP3A11, CYP2A5, CYP1A2, CYP2C54, cytochrome b5 type A (CYB5A), carboxylesterase 1 (CES1), POR, GST alpha 3 (GSTA3) and alpha 4 (GSTA4), GST mu 1 (GSTM1), GST mu 3 (GSTM3), GST mu 5 (GSTM5), UDP-glucose 6-dehydrogenase (UGDH), and paraoxonase 1 (PON1) was demonstrated by proteome analysis.
Primary Insecticide class Mode of Vulnerable neurological action genetic target subpopulations AChE OP Inhibition PON1 polymorphisms CB Inhibition Voltage-gated OC Modified SCN1A, SCN1B sodium gating channel kinetics pyrethrin/pyrethriod Modified HCE1 (CES1) gating kinetics GABA-gated Cyclodienes (a form Antagonism HCE2 (CES2) GABA chloride of OC) receptor channel polymorphisms Phenylpyrazole Antagonism nAChR(a) Neonicotinoid Agonism Haploinsufficiency of [alpha]7 nAChR Adapted from Scharf (2003).