chronic lymphocytic leukemia

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Noun1.chronic lymphocytic leukemia - chronic leukemia characterized by lymphoblast-like cells; more common in older men
chronic leukemia - slowly progressing leukemia
References in periodicals archive ?
Molecular genetic studies by FISH for CLL associated prognostic abnormalities detected a deletion in 13q.
Imbruvcca is now recommended by the SMC for adult patients with for CLL, for whom fludarabine-based regimens are deemed unsuitable.
Cytogenetic abnormalities, such as deletions in 13q (13q−), 11q (11q−), and 17p (17p−), are critical events in the pathogenesis of CLL and important predictors of disease progression and survival,[sup][5] as detected by interphase fluorescence in situ hybridization (I-FISH).
While CLL constitutes approximately 30% of all leukemia cases in the Western countries, its incidence has been reported to be about 4/100,000 in the United States and 5/100,000 in Europe.
All patients of CLL from October 2008 to September 2013 were studied.
The aim of the present study was to investigate altered levels of Dicer miRNA in patients with ALL and CLL.
Croce's group analyzed many cases of CLL and found that in approximately 70% of them miR-15a/16-1 were lost (2, 4).
CLL is the most common form of adult leukaemia in the Western world1,2 and the second most common haematological malignancy3.
Gisela Satherley, from Maerdy, Rhondda, has battled with CLL for the past eight years and was recently given between four and eight weeks to live.
We look forward to a rewarding and productive partnership with Roche to evaluate our product with GAZWA in order to deliver new treatment options to patients with NHL and CLL.
They were able to disrupt the activity of a pathway (NF-kappaB) that ensures the survival and resistance of the CLL cells in such microenvironments.