cytomegalovirus

(redirected from CMV disease)
Also found in: Thesaurus, Medical, Encyclopedia.

cy·to·meg·a·lo·vi·rus

 (sī′tə-mĕg′ə-lō-vī′rəs)
n. Abbr. CMV
Any of a group of herpesviruses that attack and enlarge epithelial cells. Such viruses also cause a disease of infants characterized by circulatory dysfunction and microcephaly.

cytomegalovirus

(ˌsaɪtəʊˈmɛɡələʊˌvaɪrəs)
n
(Microbiology) a virus of the herpes virus family that may cause serious disease in patients whose immune systems are compromised. Abbreviation: CMV

cy•to•meg•a•lo•vi•rus

(ˌsaɪ toʊˌmɛg ə loʊˈvaɪ rəs)

n., pl. -rus•es.
a herpesvirus that produces abnormal enlargement of epithelial cells, usu. mildly infectious but a cause of pneumonia in immunodeficient persons and severe systemic damage in the newborn.
[1960–65]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cytomegalovirus - any of a group of herpes viruses that enlarge epithelial cells and can cause birth defects; can affect humans with impaired immunological systems
herpes virus, herpes - any of the animal viruses that cause painful blisters on the skin
Translations

cy·to·meg·a·lo·vi·rus

n. citomegalovirus, grupo de virus pertenecientes a la familia Herpesviridae que infectan humanos y otros animales, y son causantes de la enfermedad de inclusión citomegálica.

cytomegalovirus (CMV)

n citomegalovirus m (CMV)
References in periodicals archive ?
In addition, many programs prevent CMV disease in high-risk populations by using medications for prophylaxis and active surveillance coupled with preemptive therapy upon detection of CMV replication.
A healthy immune system typically protects an infected person against CMV disease, but does not prevent or clear latent infection.
10] However, as CMV retinitis is asymptomatic in almost half of affected patients in the early stages of disease, [11] routine screening fundoscopy for those at high risk of CMV disease by a trained clinician, not necessarily an ophthalmologist, is necessary.
International guidelines reported that CD4 cell level is less predictive of risk for CMV disease in young infants with HIV, and CMV infection can occur in HIV-infected children with higher CD4 counts.
sup][11] CMV disease is usually seen in immunocompromised patients with HIV infection or postorgan transplantation under immunosuppressant.
For patients with evidence of CMV viraemia and attributable symptoms or signs, initiate antiviral therapy; and strong consideration should be given to interrupting Zydelig until CMV disease has resolved.
While preemptive therapy (treatment when CMV DNA is detected in the blood) with antiviral medicines can reduce the incidence of CMV disease, CMV reactivation post-HSCT is associated with higher mortality despite the use of preemptive therapy.
In a recent meta-analysis, ganciclovir was found to be comparable to either valganciclovir or valacyclovir regarding the prevention of CMV disease.
Suppression of the cellular immune response is the major underlying predisposing factor for CMV disease.
The School of Medicine in Cardiff has a well-established background in virology, especially CMV, and is one of only a handful of places in the UK investigating CMV disease.
It is more useful and beneficial for diagnosing CMV infection than CMV antigenemia assay or histological examination and is correlated with the clinical course or severity of CMV disease in organ transplantation or AIDS.