grog

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grog

 (grŏg)
n.
1. An alcoholic liquor, especially rum diluted with water.
2. A rum cocktail, especially when heated and made with lemon or lime juice, sugar, and cinnamon.

[After Old Grog, nickname of Edward Vernon (1684-1757), British admiral who ordered that diluted rum be served to his sailors, from grogram (from his habit of wearing a grogram cloak).]

grog

(ɡrɒɡ)
n
1. (Brewing) diluted spirit, usually rum, as an alcoholic drink
2. (Brewing) informal chiefly Austral and NZ alcoholic drink in general, esp spirits
[C18: from Old Grog, nickname of Edward Vernon (1684–1757), British admiral, who in 1740 issued naval rum diluted with water; his nickname arose from his grogram cloak]

grog

(grɒg)

n.
1. a mixture of rum and water, often flavored with lemon, sugar, and spices and sometimes served hot.
2. any alcoholic drink.
[1760–70; from Old Grog (alluding to his grogram cloak), the nickname of Edward Vernon (d. 1757), British admiral, who in 1740 ordered the mixture to be served, instead of pure spirits, to sailors]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.grog - rum cut with watergrog - rum cut with water      
rum - liquor distilled from fermented molasses
Translations
grogi
grog

grog

[grɒg] Ngrog m

grog

[ˈgrɒg] ngrog m

grog

nGrog m

grog

[grɒg] ngrog m inv
References in periodicals archive ?
Additionally, miR-192 significantly alters expression of NOD2 mRNA and protein and significantly reduces phosphorylation of NF-[kappa]B and expression of IL-8 and CXCL3 [17, 33].
Based on "omics" data which has been experimentally validated, molecules in circulating monocytes that are relevant to BMD may be categorized into processes such as apoptosis/survival (PLK3 and HSPB1), migration/chemotaxis (CXCL3, GSN, and HSPB1), adhesion (RSU1, HSPB1), transendothelial migration (ANXA2, HSPB1), differentiation into osteoclasts (STAT1, GBP1, ANXA2, and GSN), and other miscellaneous processes such as histamine biosynthesis (HDC), glucocorticoid sensitivity (GCR), regulation of oxidative stress (SOD2, GPX1), and protein folding (P4HB) and multifunctional molecules, miR-133a and miR422a (complete list of molecules identified and validated in Table 1).
Several papers demonstrated that TNF[alpha] in KC regulates different genes involved in inflammation and angiogenesis, such as IL-1, ICAM-1, VEGF [29, 30], TGF-[beta], chemokines (CCL20, CCL27, CCL5, CCL2, CXCL10, and CXCL11), and members of the CXCL8 family, including CXCL1, CXCL2, and CXCL3 [10, 22, 23].
Fifteen module-related DEGs marked as bold in Table 4 were thus obtained, including CXCL2, CXCL1, BDKRB1, LPAR1, CXCL3, FYN, COL6A2, COL18A1, COL13A1, COL5A1, TUBA1A, FDFT1, SQLE, LSS, and CDK9.
Likewise, among the top 20 upregulated genes we found 11 Wnt/[beta]-catenin target genes (Table 1 and Supplementary Table 3), including the palmitoleoyl-protein carboxylesterase Notum (ID: 303743; nominal p value = 1.5 x [10.sup.-5]; FC = 14.1), Lef1 (ID: 161452; nominal p value = 1.7 x [10.sup.-5]; FC = 2.1), Axin2 (ID: 29134; nominal p value = 1.2 x [10.sup.-4]; FC = 3.5), and the chemokine (C-X-C motif) ligand 3 Cxcl3 (ID: 171551; nominal p value = 5.2 x [10.sup.-4]; FC = 4.6).
The genes examined were tumor necrosis factor alpha (TNF-[alpha]), interferon gamma (IFN-[gamma]), and interleukin-6 (IL-6) for inflammatory cytokines and monocyte chemotactic protein-1 (MCP-1) and Chemokine (C-X-C motif) ligand 3 (Cxcl3) for chemokines.
CXCL3 gene, belonging to chemokine family, is related to inflammatory response.
The genes that were downregulated by more than 2fold included the genes encoding the cytokines chemokine (C-X-C motif) ligand 3 (CXCL3) and caprin family member 2 (CAPRIN2), the transporter component of the oligomeric golgi complex 5 (COG5), and various genes associated with transcription, kinase, ion binding, and nucleotide metabolism.
Name References Cytokines TNF-[alpha] (+) [69-71] IL-1 (+) [72-74] IL-6 [41] IL-8 (CXCL18) [75, 76] IL-15 [77] IL-17 [78] IL-18 (+) [79-82] Chemokines CXCL1 [83, 84] CXCL2 [83, 84] CXCL3 [83-86] CXCL5 [83, 84] CXCL6 [83, 84] CXCL7 [83, 84] CXCL9 [83] CXCL12 (SDF-1) [87, 88] CCL2 (MCP-1) [89, 90] (+) Also antiangiogenic activity has been reported.
These include Bcl2, CCND1, CXCL1, CXCL3, IL-18, IL-6, IRF1, NF-KB1, PTGS2, TNF-[alpha], TNFSF10, TRADD, and TRAF1.
Among genes ascribed to the immune response, twenty Th17-lymphocyte-related genes were upregulated including interleukin 6 signal transducer, IL6ST, chemokine (C-C motif) ligand 20, CCL20, suppressor of cytokine signaling 3, SOCS3, chemokine (C-X-C motif) ligand 1, CXCL1, chemokine (C-X-C motif) ligand 2, CXCL2, chemokine (C-X-C motif) ligand 3, CXCL3, inducible T cell costimulator, ICOS, intercellular adhesion molecule 1, ICAM1, interleukin 8, IL-8, interleukin 1 beta, and IL-1B (see also Table 2).
The liver transcriptional expressions of CXCL1, CXCL2, CXCL3, CXCL5, CCL2, and CCL6 significantly increased in WT and IL-33 KO mice during L2-MHV3-induced hepatitis compared to those in control PBS-injected mice as soon as 48 h PI and at 72 h PI (Figures 6(c), 6(d), 6(e), 6(f), 6(g), and 6(h)).