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Any of a group of proteins that span the plasma membrane of eukaryotic cells and, in the presence of calcium, bind to identical proteins in adjacent cells, thus linking cells together in tissues.

[Blend of ca(lcium) + adher(e) + -in.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
In addition to GJB2, >80 mutations in MYO7A (OMIM: 276903) encoding myosin VIIA have also been linked with syndromic and NSHL.11 MYO7A co-ordinates between the transduction channel and stereocilia membrane and interact with hair cells by associating with cadherin molecules.
Cell Cycle DNA test plus reagent Kit and Annexin V apoptosis detection kit were from BD, Pharmingen (USA) and phalloidine, Anti-E cadherin were obtained from Thermo Scientific (USA).
Several studies have established a link between the gene that encodes T-cadherin, cadherin 13, and various metabolic diseases [32-34].
Caption: Figure 7: Effects of SB-431542 treatment on the expression of E- cadherin, vimentin, and collagen type by RT-PCR and Western blot.
The topics include the integration of cadherin adhesion and cytoskeleton at adherens junction, making connections: guidance cues and receptors at non-neural cell-cell-junctions, tuning collective cell migration by cell-cell junction regulation, beyond cell-cell adhesion: sensational cadherins for hearing and balance, and the loss of E-cadherin-dependent cell-cell adhesion and the development and progression of cancer.
All CDH genes (n = 27) screened in this study include CDH1 (E-cadherin), CDH2 (N-cadherin), CDH3 (P-cadherin), CDH4 (R-cadherin), CDH5 (VE-cadherin), CDH6 (K-cadherin), CDH7 (cadherin 7), CDH8 (cadherin 8), CDH9 (T1-cadherin), CDH10 (T2-cadherin), CDH11 (OB-cadherin), CDH12 (N-cadherin 2), CDH13 (H-cadherin), CDH15 (M-cadherin), CDH16 (KSP-cadherin), CDH17 (LI-cadherin), CDH18 (cadherin 18), CDH20 (cadherin 20), PCDHGA12 (CDH21), CDH22 CDH23 CDH24 DCHS1 (CDH19, or CDH25), CDH26 DCHS2 (CDH27), CDHR3 (CDH28), and CDHR4 (CDH29).
The loss of E- Cadherin, alpha- and beta- catenin expression is associated with metastasis and poor prognosis in invasive breast cancer.
The GLE suppressed the TGF-[beta]1 -induced morphological changes and the changes in cadherin expression, and also inhibited the formation of F-actin stress fibers, which are a hallmark of EMT.
E-cadherin is a member of the cadherin superfamily, serving as the main epithelial intercellular adhesion molecule.
Center cells lost the expression of octamer-binding transcription factor 4 (OCT4) and epithelial cadherin (E-cadherin) faster than perimeter cells, which are critical to the development of heart tissue.