However, long-acting calcium channel blockers
have been found to be generally safe and effective (Eisenberg, Brox, and Bestawros, 2004).
The cardiovascular drugs that have the most favorable profile would be the class of alpha-blockers, ACE inhibitors and ARBs--venodilators, nitrates and slow calcium channel blockers
(with the exception of verapamil, which may cause a significant decrease in heart rate response at peak exercise.
Commonly recommended medications include beta blockers, calcium channel blockers
and tricyclic antidepressants.
The beneficial effect of calcium channel blockers
is mediated via their peripheral vasodilatory, antiplatelet, and antileukocytic effects.
Variation in nonchronic therapy classes was greatest for cough/cold/allergy medications and in chronic classes for calcium channel blockers
Benoff has for many years investigated whether calcium channel blockers
commonly prescribed for high blood pressure and heart disease can serve as male contraceptives.
Long-acting calcium channel blockers
are significantly less effective than other antihypertensive agents in reducing the disease's major cardiovascular complications, according to a new metaanalysis.
A large-scale study in Sweden found a significant link between the use of calcium channel blockers
and the incidence of suicide.
Calcium channel blockers
are typically used to treat hypertension and have been viewed with caution in the United States since 1995, when the initial findings of several scattered studies found a possible link to heart attacks, strokes, cancer, gastrointestinal bleeding, and perhaps even Parkinson's disease, according to Brant S.
One drug, an angiotensin-converting enzyme (ACE) inhibitor, has proven effective in preventing progression to stages IV and V Calcium channel blockers
, another class of antihypertensive drugs, also show promise.
The researchers had raised the question about the relative safety of calcium channel blockers
Beta blockers, even the selective types, and oral decongestants can cause worsening peripheral vasoconstriction, and should be avoided; in the diabetic, beta blockers should be replaced by calcium channel blockers
for angina or high blood pressure.