folinic acid

(redirected from Calcium folinate)
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Related to Calcium folinate: folinic acid, leucovorin
Translations

folinic acid

n ácido folínico
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References in periodicals archive ?
Two different chemotherapeutic protocols were applied: (a) 5-fluorouracil (5-FU) and calcium folinate (six cycles of monthly bolus intravenous calcium folinate 20 mg/[m.sup.2]/day, days 1-5 and 5-FU 400-425 mg/[m.sup.2]/day, days 1-5); and (b) capecitabine regimen: orally at a dosage of 1000 mg/[m.sup.2] twice daily on days 1-14 of a three-week period.
(3) Bone myelosuppression, pancytopenia, agranulocytosis, inflammation and necrotic changes in mucous tissues, liver cell necrosis and hepatic cirrhosis, pulmonary fibrosis, disorders of kidney function, vasculitis and skin lesions are some side effects that may occur during the use of MTX.[1] When MTX is used in high doses, calcium folinate is the recommended rescue therapy.
Leucovirin (calcium folinate) in "antifreeze" poisoning.
Teva therefore agreed to dispose of the carboplatin and cisplatin businesses in the Czech Republic, Hungary and Slovenia, the fluorouracil business in the Czech Republic, the methotrexate businesses in the Czech Republic and Hungary, the paclitaxel businesses in the Czech Republic and Poland, the calcium folinate business in Poland, the tamoxifen business in Slovakia and Barr's calcium folinate business in the Czech Republic.
The FOLFIRI-3 regimen was administered every 14 days: on day 1 irinotecan, 100 mg/[m.sup.2], as a 1-hour infusion running concurrently with calcium folinate 400 mg/[m.sup.2], as a 2-hour infusion, followed by 5-FU, 2400 mg/[m.sup.2], as a 46-hour infusion.
The MTX was discontinued, calcium folinate was commenced and the dose of corticosteroids was increased.