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n. pl. Calusa or Ca·lu·sas
1. A member of a Native American people formerly inhabiting the southwest coast of Florida from Tampa Bay to the Florida Keys. The Calusa were extinct by the mid-1700s.
2. The extinct language of the Calusa, of unknown linguistic affiliation.

[Calusa, fierce people (sense uncertain); perhaps akin to Choctaw kallo, strong.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
Due in large part to the support of the Bishop of Santiago de Cuba, Juan Garcia de Palacios, the campaign to establish missions among the Ais and Calusa in south Florida was revived.
The Mares' Novices' Chase Final (1.45) can go to CALUSA CRYSTAL.
Philip Hobbs' Calusa Crystal looks to hold a straightforward task in the EBF/TBA Mares' Novices' Chase at Warwick.
2.00 Golden Square; 2.30 Double Pride; 3.00 Calusa Crystal; 3.30 Pantalaimon (NAP); 4.00 Quipe Me Posted; 4.30 Back Exit; 5.00 Kadenis.
Alan King's DOUBLE PRIDE (2.30) is strongly fancied to follow up his recent win here under a penalty, while Richard Johnson and TOT OF THE KNAR (3.00) look to have Calusa Crystal to beat in a weak mares' novices chase.
ROCKAVON (of the Sunday Mail) Today's nap: EXMOOR RANGER (3.40 Sandown) Tomorrow's nap: STONEY'S TREASURE (3.20 Fontwell) KLONDYKE CALUSA CRYSTAL (1.55 Doncaster) ALEGRALIL (2.55 Doncaster) STRATEGIC APPROACH (3.10 Sandown) POT LUCK Sandown placepot 1.30 -1; 2.05 -3; 2.35 -4; 3.10 -8, 9; 3.40 -4, 6; 4.15 -2, 7.
The well-regarded Calusa Crystal has been nothing short of a revelation over the last 10 months.
Eased down on the runin, he beat Calusa Crystal by 28 lengths and though the Novices' Chase is much tougher, he is strongly fancied to come out on top again.
FONTWELL: 2.00 Little Firecracker, 2.30 Calusa Caldera, 3.00 There's No Panic, 3.35 Tot of The Knar, 4.10 Ashmolian, 4.45 Zorro De La Vega, 5.20 Alverstone.
This looks an ideal opportunity for the six year old Calusa Caldera finally broke his duck over fences at Ffos Las recently and he could follow up in the Crabbies Alcoholic Ginger Beer Novices' Chase at Fontwell.
Holly Moulder author; Teri Wilson illustrator; EYES OF THE CALUSA; White Pelican Press (Middle Readers:Fiction) $0.00 ISBN: 9780979040504
The following chapter focuses on encounters between the Jesuits and the Calusa of Florida.