antigen

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Related to Cancer Antigen: Cancer antigen 19-9, Cancer antigen 15-3

an·ti·gen

 (ăn′tĭ-jən) also an·ti·gene (-jēn′)
n.
A molecule that is capable of binding to an antibody or to an antigen receptor on a T cell, especially one that induces an immune response. An antigen is usually a foreign substance, such as a toxin or a component of a virus, bacterium, or parasite.

an′ti·gen′ic (-jĕn′ĭk) adj.
an′ti·gen′i·cal·ly adv.
an′ti·ge·nic′i·ty (-jə-nĭs′ĭ-tē) n.

antigen

(ˈæntɪdʒən; -ˌdʒɛn) or

antigene

n
(Biochemistry) a substance that stimulates the production of antibodies
[C20: from anti(body) + -gen]
ˌantiˈgenic adj
ˌantiˈgenically adv

an•ti•gen

(ˈæn tɪ dʒən, -ˌdʒɛn)

n.
1. any substance that can stimulate the production of antibodies and combine specifically with them.
2. any commercial substance that, when injected or absorbed into animal tissues, stimulates the production of antibodies.
3. antigens of a particular type collectively.
[1905–10; anti (body) + -gen]
an`ti•gen′ic, adj.
an`ti•gen′i•cal•ly, adv.
an`ti•ge•nic′i•ty (-dʒəˈnɪs ɪ ti) n.

an·ti·gen

(ăn′tĭ-jən)
A substance that stimulates the production of an antibody when introduced into the body. Antigens include toxins, bacteria, viruses, and other foreign substances. See Note at blood type.

antigen

A molecule recognized as foreign by the body’s immune system, causing the release of antibodies.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.antigen - any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)
substance - a particular kind or species of matter with uniform properties; "shigella is one of the most toxic substances known to man"
immunizing agent, immunogen - any substance or organism that provokes an immune response (produces immunity) when introduced into the body
immunology - the branch of medical science that studies the body's immune system
agglutinogen - any substance that acts as an antigen to cause agglutinin production
fetoprotein, foetoprotein - any of several antigens that occur naturally in the fetus and sometimes in adults with cancer
anatoxin, toxoid - a bacterial toxin that has been weakened until it is no longer toxic but is strong enough to induce the formation of antibodies and immunity to the specific disease caused by the toxin; "diphtheria toxoid"
antigenic determinant, epitope, determinant - the site on the surface of an antigen molecule to which an antibody attaches itself
Rh, Rh factor, rhesus factor - a blood group antigen possessed by Rh-positive people; if an Rh-negative person receives a blood transfusion from an Rh-positive person it can result in hemolysis and anemia
Translations
antigen
antigeeni
antigén
antígeno
antigen
antigen

antigen

[ˈæntɪdʒən] Nantígeno m

antigen

[ˈæntɪdʒən] nantigène manti-hero antihero [ˈæntihɪərəʊ] nantihéros m

antigen

nAntigen nt

antigen

[ˈæntɪdʒən] nantigene m

an·ti·gen

n. antígeno, sustancia tóxica que estimula la formación de anticuerpos;
carcinoembriogenic ______ carcinoembriogénico.

antigen

n antígeno; carcinoembryonic — antígeno carcinoembrionario; prostate-specific — (PSA) antígeno prostático específico (APE)
References in periodicals archive ?
As described in detail below, we found that the CUZD1 ELISA did not recognize the CUZD1 protein, but instead it recognized another protein, mucin 16 (also known as CA125), which is an established cancer antigen known to be increased in several cancer types (ovarian, pancreatic, and lung) (8).
2] Nonstandard abbreviations: CA125, cancer antigen 125; PSA, prostate-specific antigen; CEA, carcinoembryonic antigen.
The Cancer Vac immunotherapy involves collecting blood from a patient, extracting a special type of white blood cell from the blood and then "loading" the isolated cells with a vaccine (comprising a mixture of a cancer antigen and a sugar that is used to enhance uptake of the vaccine).
The Lm Technology, using bioengineered live attenuated Listeria monocytogenes bacteria, is the only known cancer immunotherapy agent shown in preclinical studies to both generate cancer fighting T-cells directed against a cancer antigen and neutralize Tregs and myeloid-derived suppressor cells (MDSCs), that protect the tumor microenvironment from immunologic attack and contribute to tumor growth.
A promising new prostate cancer marker, PCA3 (prostate cancer antigen 3), has recently become available, and its utility for predicting short-term biopsy progression has been studied in an active surveillance program (2).
Our achievement of this milestone represents continued advancement of our lung cancer antigen discovery program," said Steven Gillis, Ph.
Santa Monica, CA; 310-820-8029), a privately-held biotechnology company, announced a research collaboration, option and license agreement under which the parties will use Abgenix's human antibody technologies to discover and develop fully human monoclonal antibody therapies against selected cancer antigen targets supplied by Agensys.
At that point, virtually every potential breast cancer antigen will be known or will be knowable," he noted.
Cancer antigen 125 (CA 125) (1-3) is commonly increased in liver cirrhosis and increased even more in ascitic fluid (4-6).
Thus, survivin is considered a major cancer antigen.
RM-1929 targets a specific cancer antigen that is highly expressed in carcinomas allowing treatment of a number of different cancer types, including cancers of the head and neck, esophagus, lung, colon, and pancreas.