Declines to revenue attributable to key products during the quarter, excluding the impact of foreign currency translation, included a $2.2 million decrease from Carbimazole
; a $2.1 million decrease from Liothyronine Sodium; a $1.8 million decrease from Nitrofurantoin; a $1.5 million decrease from Levothyroxine Sodium and a $1.2 million decrease from Cyclizine Hydrochloride.
A 25-year-old primigravida female presented to the emergency room with amenorrhoea since 10 weeks and vaginal bleeding since 6 hours.The patient had Graves' disease without symptoms of hoarseness or dysphagia, and consuming carbimazole
Spontaneous reporting of adverse reactions to carbimazole
and propylthiouracil in the UK.
Concomitant agranulocytosis and hepatotoxicity after treatment with carbimazole
. Ann Pharmacother 2006;40:2059-63.
All of our patients were on antithyroid medication (Carbimazole
) prior to RAI as per titration method according to American Thyroid Association(ATA) guidelines10 for the last 2-6 months and it was stopped five days before RAI.
He was commenced on IV hydrocortisone, carbimazole
, oral Lugol's iodine, propranolol, Cardiprin, warfarin, and oral mononitrates.
The patient was discharged home the next day on Carbimazole
20 mg twice a day and Propranolol 20 mg three times a day.
However, it is not clearly stated whether the OD-MMI and DD-MMI regimens are equally effective especially when using MMI at the currently recommended lower daily dosage of 15 mg as the evidences supporting the equal effectiveness of both regimens were based on only few studies that used unequal [5, 6] or high daily dosages of MMI  or carbimazole
[17, 18] in comparison between the OD-MMI and DD-MMI regimens.
Fifty percent of pre-existing GD patients who were thyrotoxic at first presentation were rendered euthyroid at delivery with the appropriate use of carbimazole
only (Table 3).
* Pregnant women on MMI (methimazole) or CMZ (carbimazole
) should be shifted to PTU as soon as possible.
(69) Her systemic and ocular diseases were treated successfully with oral carbimazole
and selenium, respectively.
She was rendered euthyroid with medical therapy (carbimazole