Cardio-specific beta-blockers may be beneficial as they inhibit the vestibular sympathetic cardioinhibitory
reflex as has been suggested  and may be effective in such patients in whom autonomic nervous activity is altered as in some patients with migraine and VDA.
Autonomic and electro-cardiographic changes in cardioinhibitory
She first passed out as a child but it took more than a decade before she was given a proper diagnosis of cardioinhibitory
vasovagal syndrome in May 2011.
This caused increased frequency of cardioinhibitory
impulses via the vagus nerve to the SA node of the heart leading to decreased heart rate [13, 14].
The responses were classified as vasoinhibitory, cardioinhibitory
, or mixed inhibitory.
As the increased intrapulmonary pressure causes the excitation of stretch receptors in the lung and nerve impulses generated converges on the cardioinhibitory
area in the medulla.
Fortunately, the syncopal episodes responded to permanent cardiac pacing, supporting the hypothesis that syncope was predominately the result of sinus arrest (cardioinhibitory
response), as opposed to dysautonomia-associated hypotension (vasodepressor response), for which the role of cardiac pacing is poorly defined.
With surgical decompression or denervation, the cardioinhibitory
and vasodepressor response to compression can be reversed [2, 3].
Hemodynamic classification was recorded as mixed neurocardiogenic response, vasodepressor, or cardioinhibitory
. Within our laboratory, standardized definitions of each response were used.
When comparing the spectral characteristic charts before and after the rehabilitation treatment and those of the control (healthy person) groups, a pronounced decrease in the activity of ergotropic and humoral-metabolic mechanisms of HR regulation (VLF from 55 to 38%), a decrease in the activity of the sympathetic centers of the macromyelon (LF from 39 to 30%), and an increase in the activity of the parasympathetic centers of the macromyelon (HF from 6 to 32%) are observed, which indicate the predominance of the total score of parasympathetic (cardioinhibitory
) and sympathetic (cardiac stimulant) centers of the macromyelon over the central mechanisms of HR regulation.
(2) In some cases, heart conditions require cardiac surgery and/or dual-chamber cardiac pacing (in the case of cardioinhibitory
carotid sinus hypersensitivity).
Tota, "The emerging cardioinhibitory
role of the hippocampal cholinergic neurostimulating peptide," Journal of Pharmacology and Experimental Therapeutics, vol.