Mussels have a high number of unique chemical functional groups called catechols
, which are used to prime and promote adhesion to wet mineral surfaces.
Pharmacodynamics are affected by many factors; for opiates these include differences in receptor morphology (OPRM gene variant SNP 118 A/G), differences in target site concentrations of drug (ABCB 1/MDR 1 transporter), or effects downstream from drug reaching receptors and binding such as differences in COMT metabolism of catechols
(472 G>A SNP).
Specifically, phenolic compounds with two or more vicinal hydroxy benzyl moieties in their structure, such as catechols
and pyrogallols, were examined for their ability to give spectral bathochromic shift phenomena when mixed with iron salts.
sources and significance of plasma levels of catechols
and their metabolites in humans.
Literature has revealed that catechols
are good substrates for catechol
-O-methyltransferase and are susceptible to methylation.
2]-dependent oxidation of catechols
in quinones, and may synergistically act with POD, promoting its activation through the generation of [H.
Tomchick, "Enzymatic O-methylation of epinephrine and other catechols
," The Journal of Biological Chemistry, vol.
vanbaalenii PYR-1 may play an important role in the detoxification of PAH catechols
The degree of quatemization was estimated to be 30 catechols
and 185 sulfobetaines units per PDMA chain.
The formed catechols
are conjugated with either glucuronic acid or sulphate.
This volume presents information on the synthetically useful protective groups in chemical reactions, focusing on major functional groups: the hydroxyl group, phenols and catechols
, the carbonyl group, the carboxyl group, the thiol group, the amino group, the alkyne-CH, and the phosphate group.
From the 12 cases assessed (including our present case), 5 showed increased urine catechols
or its metabolites.